Evaluation of pyridoindoles, pyridylindoles and pyridylpyridoindoles as matrices for ultraviolet matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

In an effort to gain an understanding of the processes governing ultraviolet matrix-assisted laser desorption/ionization (UV-MALDI), direct comparison was made of the mass spectra of proteins, carbohydrates and synthetic polymers (polyethylene glycol, polyester and polyamide) by using pyridylindoles...

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Autor principal: Nonami, H.
Otros Autores: Wu, F., Thummel, R.P, Fukuyama, Y., Yamaoka, H., Erra-Balsells, R.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2001
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Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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024 7 |2 scopus  |a 2-s2.0-0035215039 
024 7 |2 cas  |a 2,5-dihydroxybenzoic acid, 490-79-9; Carbohydrates; Drug Combinations; Gentisates; harman, 486-84-0; Harmine, 442-51-3; Hydroxybenzoic Acids; Indoles; Maneb, 12427-38-2; Polymers; Proteins; Pyridines; pyrifenox-mancozeb; Zineb, 12122-67-7 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a RCMSE 
100 1 |a Nonami, H. 
245 1 0 |a Evaluation of pyridoindoles, pyridylindoles and pyridylpyridoindoles as matrices for ultraviolet matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 
260 |c 2001 
270 1 0 |m Erra-Balsells, R.; Dep. Quím. Org., FCEyN, UBA, c.c. 74 - suc. 30, 1430 Buenos Aires, Argentina; email: erra@qo.fcen.uba.ar 
506 |2 openaire  |e Política editorial 
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504 |a Nonami, H., Fukui, S., Erra-Balsells, R., (1997) J. Mass Spectrom., 32, p. 287 
504 |a Nonami, H., Tanaka, K., Fukuyama, Y., Erra-Balsells, R., (1998) Rapid Commun. Mass Spectrom., 12, p. 285 
504 |a Nonami, H., Orcoyen, M., Fukuyama, Y., Biondic, M.C., Erra-Balsells, R., (1998) An. Asoc. Quim. Argentina, 85, p. 81 
504 |a Tanaka, K., Nonami, H., Fukuyama, Y., Erra-Balsells, R., (1998) Proc. 46th ASMS Conf. Mass Spectrometry and Allied Topics, p. 1016 
504 |a Erra-Balsells, R., Kolender, A., Matulewicz, M.C., Nonami, H., Cerezo, A.S., (2000) Carbohydr. Res., 329, p. 157 
504 |a Iglesias, L.F., Fukuyama, Y., Nonami, H., Erra-Balsells, R., Baldessari, A., (1999) Biotech. Tech., 13, p. 923 
504 |a Eisenberg, P., Erra-Balsells, R., Lucas, J.C., Mauri, A.N., Nonami, H., Riccardi, C.C., Williams, R.J.J., (2000) Macromolecules, 33, p. 1940 
504 |a Orgueira, H.A., Erra-Balsells, R., Nonami, H., Varela, O., (2000) Macromolecules, 34, p. 687 
504 |a Naxing, X., Huang, Z.H., Watson, J.T., Gage, D.A., (1997) J. Am. Soc. Mass Spectrom., 8, p. 116 
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504 |a Allwood, D.A., Dyer, P.E., (2000) Chem. Phys., 261, p. 457 
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520 3 |a In an effort to gain an understanding of the processes governing ultraviolet matrix-assisted laser desorption/ionization (UV-MALDI), direct comparison was made of the mass spectra of proteins, carbohydrates and synthetic polymers (polyethylene glycol, polyester and polyamide) by using pyridylindoles, pyridoindoles and pyridylpyridoindoles as UV (337 nm)-MALDI-TOFMS matrices in positive and negative ion mode. In order to study the combined effect of the indole N-H and the pyridine nitrogen of the MALDI matrix on the desorption/ionization process in MALDI, compounds were selected that include either or both of these functions in their structure. Within the compounds studied only those that possess simultaneously both functions in a 1,4-relation behave as very good matrices for proteins. These compounds also work as matrices for some carbohydrates and synthetic polymers used as analytes in the present study. Some of the compounds were also found to be useful for the post-source decay (PSD) analysis of cyclodextrins in positive and negative ion mode. In several cases we also examined the matrix behavior of the corresponding N-methylindole derivatives. Copyright © 2001 John Wiley & Sons, Ltd.  |l eng 
593 |a Plant Biophysics/Biochemistry Research Laboratory, College of Agriculture, Ehime University, 3-5-7 Tarumi, Matsuyama 790-8566, Japan 
593 |a Department of Chemistry, University of Houston, Houston, TX 77204-5641, United States 
593 |a Shimadzu Coorporation, 1 Nishinokyo-Kuwabaracho, Nakagyo-ku, Kyoto 604-6511, Japan 
593 |a Departamento de Química Orgánica, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, c.c. 74 - suc. 30, 1430 Buenos Aires, Argentina 
593 |a Dep. Quím. Org., FCEyN, UBA, c.c. 74 - suc. 30, 1430 Buenos Aires, Argentina 
690 1 0 |a 2,5-DIHYDROXYBENZOIC ACID 
690 1 0 |a BIPYRIDINE DERIVATIVE 
690 1 0 |a CARBOHYDRATE 
690 1 0 |a CARBOLINE DERIVATIVE 
690 1 0 |a CYCLODEXTRIN 
690 1 0 |a GENTISIC ACID 
690 1 0 |a HARMAN 
690 1 0 |a HARMINE 
690 1 0 |a HYDROGEN 
690 1 0 |a HYDROXYBENZOIC ACID DERIVATIVE 
690 1 0 |a INDOLE DERIVATIVE 
690 1 0 |a MANEB 
690 1 0 |a NITROGEN 
690 1 0 |a POLYMER 
690 1 0 |a PROTEIN 
690 1 0 |a PYRIDINE DERIVATIVE 
690 1 0 |a PYRIFENOX MANCOZEB 
690 1 0 |a PYRIFENOX-MANCOZEB 
690 1 0 |a ZINEB 
690 1 0 |a ARTICLE 
690 1 0 |a CARBOHYDRATE ANALYSIS 
690 1 0 |a CHEMISTRY 
690 1 0 |a CRYSTALLIZATION 
690 1 0 |a DESORPTION 
690 1 0 |a DRUG COMBINATION 
690 1 0 |a IONIZATION 
690 1 0 |a MASS SPECTROMETRY 
690 1 0 |a METHODOLOGY 
690 1 0 |a PROTEIN ANALYSIS 
690 1 0 |a PROTEIN STRUCTURE 
690 1 0 |a ULTRAVIOLET RADIATION 
690 1 0 |a ULTRAVIOLET SPECTROPHOTOMETRY 
690 1 0 |a CARBOHYDRATES 
690 1 0 |a CRYSTALLIZATION 
690 1 0 |a DRUG COMBINATIONS 
690 1 0 |a GENTISATES 
690 1 0 |a HARMINE 
690 1 0 |a HYDROXYBENZOIC ACIDS 
690 1 0 |a MANEB 
690 1 0 |a POLYMERS 
690 1 0 |a PROTEINS 
690 1 0 |a PYRIDINES 
690 1 0 |a SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION 
690 1 0 |a SPECTROPHOTOMETRY, ULTRAVIOLET 
690 1 0 |a ZINEB 
650 1 7 |2 spines  |a INDOLES 
700 1 |a Wu, F. 
700 1 |a Thummel, R.P. 
700 1 |a Fukuyama, Y. 
700 1 |a Yamaoka, H. 
700 1 |a Erra-Balsells, R. 
773 0 |d 2001  |g v. 15  |h pp. 2354-2373  |k n. 23  |p Rapid Commun. Mass Spectrom.  |x 09514198  |t Rapid Communications in Mass Spectrometry 
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