Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland
The effect of melatonin on in vivo γ-aminobutyric acid (GABA) accumulation in several brain regions was determined by measuring the increase of GABA levels following inhibition of GABA transaminase. A single melatonin injection (25-300 μg/kg) augmented significantly, by 17-20%, GABA accumulation in...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
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1986
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08119caa a22010337a 4500 | ||
|---|---|---|---|
| 001 | PAPER-18145 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204931.0 | ||
| 008 | 190411s1986 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0023022057 | |
| 024 | 7 | |2 cas |a 4 amino 5 hexynoic acid, 57659-38-8; 4 aminobutyrate aminotransferase, 9037-67-6; 4 aminobutyric acid, 28805-76-7, 56-12-2; melatonin, 73-31-4; 4-amino-5-hexynoic acid, 57659-38-8; 4-Aminobutyrate Transaminase, EC 2.6.1.19; Aminocaproic Acids; gamma-Aminobutyric Acid, 56-12-2; Melatonin, 73-31-4 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a BRREA | ||
| 100 | 1 | |a Rosenstein, R.E. | |
| 245 | 1 | 0 | |a Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland |
| 260 | |c 1986 | ||
| 270 | 1 | 0 | |m Cardinali, D.P.; Centro de Estudios Farmacológicos y de Principios Naturales, CEFAPRIN, Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Acun˜a-Castroviejo, Lowenstein, Rosenstein, Cardinali, Diurnal rhythm of benzodiazepine binding in rat cerebral cortex: disruption by pinealectomy (1986) J. Pineal Res., 3, pp. 101-109 | ||
| 504 | |a Acun˜a-Castroviejo, Rosenstein, Romeo, Cardinali, Changes in gamma-aminobutyric acid high affinity binding to cerebral cortex membranes after pinealectomy or melatonin administration to rats (1986) Neuroendocrinology, 43, pp. 24-31 | ||
| 504 | |a Anton-Tay, Melatonin effects on brain function (1974) Adv Biochem Psychopharmacol, 11, pp. 315-324 | ||
| 504 | |a Bernasconi, Bittiger, Heid, Martin, Determination of GABA levels by a3H muscimol radioreceptor assay (1980) J. Neurochem., 34, pp. 614-618 | ||
| 504 | |a Bertilsson, Mao, Costa, Applications of principles of steady-state kinetics to the estimation of gamma aminobutyric acid turnover rate in nuclei of rat brain (1977) J. Pharmacol. Exp. Ther., 200, pp. 277-284 | ||
| 504 | |a Cardinali, Vacas, Lowenstein, Melatonin action on brain: presumptive receptors and second messengers (1985) The Pineal Gland, Current State of Pineal Research, pp. 273-290. , B. Mess, Cs. Rúzsás, P. Pévet, Akadémiai Kiadó, Budapest | ||
| 504 | |a Ebadi, Regulation of the synthesis of melatonin and its significance to neuroendocrinology (1984) The Pineal Gland, pp. 1-37. , R.J. Reiter, Raven Press, New York | ||
| 504 | |a Elias, Valenta, Szekeres, Grossman, Regulatory role of gamma-aminobutyric acid in pituitary hormone secretion (1982) Psychoneuroendocrinology, 7, pp. 15-30 | ||
| 504 | |a Goldman, The physiology of melatonin (1983) Pineal Research Reviews, 1, pp. 145-182. , R.J. Reiter, Alan R. Liss, New York | ||
| 504 | |a Gomes, Trolin, GABA turnover in mouse brain: agreement between the rate of GABA accumulation after aminooxyacetic acid and the rate of disappearance after 3-mercaptopropionic acid (1982) J. Neural Transm., 54, pp. 265-274 | ||
| 504 | |a Graham, Aprison, Fluorimetric determination of aspartate glutamate and γ-aminobutyrate in nerve tissue using enzymic methods (1966) Analyt. Biochem., 15, pp. 487-497 | ||
| 504 | |a Holloway, Grota, Brown, Immunohistochemical assessment of melatonin binding in the pineal gland (1985) J. Pineal Res., 2, pp. 235-251 | ||
| 504 | |a Jung, Lippert, Metcalf, Schechter, Böhlen, Sjoerdsma, The effect of 4-amino-hex-5-ynoic acid (γ-acetylenic GABA, γ-ethynyl GABA), a catalytic inhibitor of GABA transaminase, on brain GABA metabolism in vivo (1977) J. Neurochem., 28, pp. 717-723 | ||
| 504 | |a Karsch, Bittman, Foster, Goodman, Legan, Robinson, Neuroendocrine basis of seasonal reproduction (1984) Rec. Progr. Horm. Res., 40, pp. 185-222 | ||
| 504 | |a Lindgren, Andén, Effect of the normal nerve impulse flow on the synthesis and utilization of GABA in the rat substantia nigra (1985) J. Neural Transm., 61, pp. 21-24 | ||
| 504 | |a Lowenstein, Rosenstein, Cardinali, Melatonin reverses pinealectomy-induced decrease of benzodiazepine binding in rat cerebral cortex (1985) Neurochem. Int., 7, pp. 675-681 | ||
| 504 | |a Mata, Schrier, Klein, Weller, Chiou, On GABA function and physiology in the pineal gland (1976) Brain Research, 118, pp. 383-394 | ||
| 504 | |a Niles, Pharmacologic effects of melatonin on acute stress-induced changes in brain γ-aminobutyric acid levels and receptors (1984) 14th Ann. Meet. Soc. Neurosci., , Anaheim, CA, Abstr. 329.12 | ||
| 504 | |a Nir, Behroozi, Assael, Ivriani, Sulman, Changes in the electrical activity of the brain following pinealectomy (1968) Neuroendocrinology, 4, pp. 122-127 | ||
| 504 | |a Philo, Reiter, Characterization of pinealectomy-induced convulsions in the Mongolian gerbil (Meriones unguiculatus) (1978) Epilepsia, 19, pp. 485-492 | ||
| 504 | |a Racagni, Apud, Cocchi, Locatelli, Muller, GABAergic control of anterior pituitary hormone secretion (1982) Life Sci., 31, pp. 823-828 | ||
| 504 | |a Reiter, Pineal gland: an intermediary between the environment and the endocrine system (1983) Psychoneuroendocrinology, 8, pp. 31-40 | ||
| 504 | |a Romijn, The pineal, a tranquillizing organ? (1978) Life Sci., 23, pp. 2257-2274 | ||
| 504 | |a Van der Heyden, Korf, Regional levels of GABA in the brain: rapid semiautomated assay and prevention of postmortal increase by 3-mercaptopropionic acid (1978) J. Neurochem., 31, pp. 197-203 | ||
| 504 | |a Wurtman, Lieberman, Melatonin secretion as a mediator of circadian variations in sleep and sleepiness (1985) J. Pineal Res., 1, pp. 301-303 | ||
| 520 | 3 | |a The effect of melatonin on in vivo γ-aminobutyric acid (GABA) accumulation in several brain regions was determined by measuring the increase of GABA levels following inhibition of GABA transaminase. A single melatonin injection (25-300 μg/kg) augmented significantly, by 17-20%, GABA accumulation in the hypothalamus and caused a dose-dependent increase of this parameter in the pineal gland. Significant rises of GABA accumulation were found in the cerebellum and cerebral cortex after administering 100-300 and 300 μg/kg of melatonin, respectively. © 1986. |l eng | |
| 593 | |a Centro de Estudios Farmacológicos y de Principios Naturales, CEFAPRIN, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CEREBELLUM |
| 690 | 1 | 0 | |a CEREBRAL CORTEX |
| 690 | 1 | 0 | |a HYPOTHALAMUS |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a PINEAL GLAND |
| 690 | 1 | 0 | |a Γ-AMINOBUTYRIC ACID (GABA) |
| 690 | 1 | 0 | |a 4 AMINO 5 HEXYNOIC ACID |
| 690 | 1 | 0 | |a 4 AMINOBUTYRATE AMINOTRANSFERASE |
| 690 | 1 | 0 | |a 4 AMINOBUTYRIC ACID |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a BRAIN CORTEX |
| 690 | 1 | 0 | |a CENTRAL NERVOUS SYSTEM |
| 690 | 1 | 0 | |a CEREBELLUM |
| 690 | 1 | 0 | |a DRUG INTERACTION |
| 690 | 1 | 0 | |a DRUG RECEPTOR BINDING |
| 690 | 1 | 0 | |a INTRAPERITONEAL DRUG ADMINISTRATION |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PINEAL BODY |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a 4-AMINOBUTYRATE TRANSAMINASE |
| 690 | 1 | 0 | |a AMINOCAPROIC ACIDS |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a BRAIN |
| 690 | 1 | 0 | |a CEREBELLUM |
| 690 | 1 | 0 | |a CEREBRAL CORTEX |
| 690 | 1 | 0 | |a GAMMA-AMINOBUTYRIC ACID |
| 690 | 1 | 0 | |a HYPOTHALAMUS |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MELATONIN |
| 690 | 1 | 0 | |a PINEAL GLAND |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RATS, INBRED STRAINS |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 700 | 1 | |a Cardinali, D.P. | |
| 773 | 0 | |d 1986 |g v. 398 |h pp. 403-406 |k n. 2 |p Brain Res. |x 00068993 |w (AR-BaUEN)CENRE-4052 |t Brain Research | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/0006-8993(86)91505-2 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00068993_v398_n2_p403_Rosenstein |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v398_n2_p403_Rosenstein |y Registro en la Biblioteca Digital |
| 961 | |a paper_00068993_v398_n2_p403_Rosenstein |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 79098 | ||