Biosynthesis of glycogen from uridine diphosphate glucose
An enzyme which leads to the formation of glycogen according to the equation: UDPG + primer → UDP + glucosyl α (1 → 4) primer has been studied. The optimal conditions for activity were determined with a partially purified preparation from rat muscle. The reaction requires the presence of a polysacch...
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| Otros Autores: | , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1959
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 03794caa a22005777a 4500 | ||
|---|---|---|---|
| 001 | PAPER-1805 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203108.0 | ||
| 008 | 190411s1959 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0000367913 | |
| 024 | 7 | |2 cas |a glycogen, 9005-79-2; Glycogen, 9005-79-2; Nucleosides; Nucleotides | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a ABBIA | ||
| 100 | 1 | |a Leloir, L.F. | |
| 245 | 1 | 0 | |a Biosynthesis of glycogen from uridine diphosphate glucose |
| 260 | |c 1959 | ||
| 270 | 1 | 0 | |m Leloir, L.F.; Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, ôbligado 2490 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a An enzyme which leads to the formation of glycogen according to the equation: UDPG + primer → UDP + glucosyl α (1 → 4) primer has been studied. The optimal conditions for activity were determined with a partially purified preparation from rat muscle. The reaction requires the presence of a polysaccharide as primer and is strongly activated by hexose 6-phosphates. Using UDPG labeled in the glucose moiety, it was found that the radioactivity was transferred to the glycogen from which it could be removed as maltose with β-amylase or as G-1-P with phosphorylase. Thus it seems that the glucose residue becomes linked α (1 → 4) to the polysaccharide. Several inhibitors were tested as well as the occurrence of the enzyme in different organs. © 1959. |l eng | |
| 536 | |a Detalles de la financiación: National Institutes of Health | ||
| 536 | |a Detalles de la financiación: U.S. Public Health Service | ||
| 536 | |a Detalles de la financiación: 1 This investigation was supported in part by a research grant National Institutes of Health, U. S. Public Health Service. z Fellow of the Consejo National de Investigaciones Cientificas 3 Investigator of the Instituto National de Microbiologia. 4 Investigator of the Comisi6n National de Energla AMmica. 6 Abbreviations used: UDPG: uridinediphosphate glucose; phate; G-l-P: glucose l-phosphate; G-6-P: glucose 6-phosphate; methyl)aminomethane; EDTA: ethylenediamine tetraacetate. | ||
| 593 | |a Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, ôbligado 2490 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a GLYCOGEN |
| 690 | 1 | 0 | |a NUCLEOSIDE |
| 690 | 1 | 0 | |a NUCLEOTIDE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a GLYCOGEN/METABOLISM |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a MUSCLE |
| 690 | 1 | 0 | |a MUSCLES/METABOLISM |
| 690 | 1 | 0 | |a NUCLEOSIDES AND NUCLEOTIDES/METABOLISM |
| 690 | 1 | 0 | |a GLYCOGEN/METABOLISM |
| 690 | 1 | 0 | |a MUSCLES/METABOLISM |
| 690 | 1 | 0 | |a NUCLEOSIDES AND NUCLEOTIDES/METABOLISM |
| 690 | 1 | 0 | |a GLYCOGEN |
| 690 | 1 | 0 | |a MUSCLES |
| 690 | 1 | 0 | |a NUCLEOSIDES |
| 690 | 1 | 0 | |a NUCLEOTIDES |
| 700 | 1 | |a Olavarría, J.M. | |
| 700 | 1 | |a Goldemberg, S.H. | |
| 700 | 1 | |a Carminatti, H. | |
| 773 | 0 | |d 1959 |g v. 81 |h pp. 508-520 |k n. 2 |p Arch. Biochem. Biophys. |x 00039861 |w (AR-BaUEN)CENRE-1377 |t Archives of Biochemistry and Biophysics | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0000367913&doi=10.1016%2f0003-9861%2859%2990232-2&partnerID=40&md5=4eebb3012aa5d9d564f4a5be0296b625 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0003-9861(59)90232-2 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00039861_v81_n2_p508_Leloir |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00039861_v81_n2_p508_Leloir |y Registro en la Biblioteca Digital |
| 961 | |a paper_00039861_v81_n2_p508_Leloir |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 62758 | ||