Adrenocorticoid action in the spinal cord: Some unique molecular properties of glucocorticoid receptors
1. Glucocorticoid hormones affect several functions of the spinal cord, such as synaptic transmission, biogenic amine content, lipid metabolism, and the activity of some enzymes (ornithine decarboxylase, glycerolphosphate dehydrogenase), indicating that this tissue is a target of adrenal hormones. 2...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Kluwer Academic Publishers-Plenum Publishers
1989
|
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 15924caa a22013817a 4500 | ||
|---|---|---|---|
| 001 | PAPER-17934 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230607131910.0 | ||
| 008 | 190411s1989 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0024339890 | |
| 024 | 7 | |2 cas |a corticosterone, 50-22-6; dexamethasone, 50-02-2; Corticosterone, 50-22-6; Dexamethasone, 50-02-2; Glucocorticoids; Receptors, Glucocorticoid; Ribonucleases, EC 3.1.- | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a CMNED | ||
| 100 | 1 | |a De Nicola, A.F. | |
| 245 | 1 | 0 | |a Adrenocorticoid action in the spinal cord: Some unique molecular properties of glucocorticoid receptors |
| 260 | |b Kluwer Academic Publishers-Plenum Publishers |c 1989 | ||
| 270 | 1 | 0 | |m De Nicola, A.F.; Laboratorio de Bioquímica Neuroendócrina, Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Beato, M., Kalimi, M., Koustan, M., Feigelson, P., Interaction of glucocorticoids with rat liver nuclei. II. Studies on the nature of the cytosol transfer factor and the nuclear acceptor site (1973) Biochemistry, 12, pp. 3372-3379 | ||
| 504 | |a Birmingham, M.K., Sar, M., Stumpf, W.E., Localization of aldosterone and corticosterone in the central nervous system, assessed by quantitative autoradiography (1984) Neurochem. Res., 9, pp. 333-50 | ||
| 504 | |a Chong, M.T., Lippman, M.E., Effects of RNA and ribonuclease on the binding of estrogen and glucocorticoid receptors from MCF-7 cells to DNA-cellulose (1982) J. Biol. Chem., 257, pp. 2996-3002 | ||
| 504 | |a Clark, C.R., MacLusky, N.J., Naftolin, F., Glucocorticoid receptors in the spinal cord (1981) Brain Res., 217, pp. 412-415 | ||
| 504 | |a Coirini, H., Marusic, E.T., De Nicola, A.F., Rainbow, T.C., McEwen, B.S., Identification of mineralocorticoid binding sites in rat brain by competition studies and density gradient centrifugation (1983) Neuroendocrinology, 37, pp. 354-360 | ||
| 504 | |a Coirini, H., Magariños, A.M., De Nicola, A.F., Rainbow, T.C., McEwen, B.S., Further studies of brain aldosterone binding sites employing new mineralocorticoid and glucocorticoid receptor markers in vitro (1985) Brain Res., 361, pp. 212-216 | ||
| 504 | |a Currie, R.A., Cidlowski, J.A., Identification of modified forms of human glucocorticoid receptors during the cell cycle (1982) Endocrinology, 110, pp. 2192-2194 | ||
| 504 | |a De Fiore, C.H., Turner, B.B., (3H)-Corticosterone binding in the caudate-putamen (1983) Brain Res., 278, pp. 93-101 | ||
| 504 | |a De Nicola, A.F., Tornello, S., Weisenberg, L., Fridman, O., Birmingham, M.K., Uptake and binding of (3H)-aldosterone by the anterior pituitary and brain regions in adrenalectomized rats (1981) Horm. Metab. Res., 13, pp. 103-106 | ||
| 504 | |a De Nicola, A.F., Ortí, E., Moses, D.F., Magariños, A.M., Coirini, H., Functions and dysfunctions of receptors for adrenal steroids in the central nervous system (1987) J. Steroid Biochem., 27, pp. 599-607 | ||
| 504 | |a Do, Y.S., Loose, D.S., Feldman, D., Heterogeneity of glucocorticoid binders: A unique and a classical dexamethasone binding sites in bovine tissues (1979) Endocrinology, 105, pp. 1055-1063 | ||
| 504 | |a Duncan, G.E., Stumpfs, W.E., Target neurons for (3H)-corticosterone in the rat spinal cord (1984) Brain Res., 307, pp. 321-326 | ||
| 504 | |a Economidis, I.V., Rousseau, G.G., Association of the glucocorticoid hormone receptor with ribonucleic acid (1985) FEBS, 181, pp. 47-82 | ||
| 504 | |a Etgen, A.M., Martin, M., Gilbert, R., Lynch, G., Characterization of corticosterone-induced protein synthesis in hippocampal slices (1980) J. Neurochem., 35, pp. 598-602 | ||
| 504 | |a Fuxe, K., Wikstrom, A.C., Okret, S., Agnati, L.F., Harfstrand, A., Yu, Z.-Y., Granholm, I., Gustafsson, J.-A., Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor (1985) Endocrinology, 117, pp. 1803-1812 | ||
| 504 | |a Ball, E.D., Glucocorticoid effects on central nervous excitability and synaptic transmission (1982) Int. Rev. Neurobiol., 23, pp. 165-195 | ||
| 504 | |a Ball, E.D., Braughler, T., Acute effects of intravenous glucocorticoid pretreatment on the in vitro peroxidation of cat spinal cord tissue (1981) Exp. Neurol., 73, pp. 321-324 | ||
| 504 | |a Hall, E.D., McGinley, P.A., Effects of a single intravenous glucocorticoid dose on biogenic amine levels in cat lumbar spinal cord (1982) J. Neurochem., 39, pp. 1787-1790 | ||
| 504 | |a Heller, C.L., Coirini, H., De Nicola, A.F., Influence of phosphatase inhibitors and nucleotides on (3H)-dexamethasone binding in cytosol of human placenta (1984) J. Steroid Biochem., 21, pp. 381-386 | ||
| 504 | |a Hutchens, T.W., Markland, F.S., Hawkins, E.F., Physicochemical analysis of reversible molybdate effects on different molecular forms of glucocorticoid receptor (1981) Biochem. Biophys. Res. Comm., 103, pp. 60-67 | ||
| 504 | |a Hutchens, T.W., Markland, F.S., Hawkins, E.F., RNA induced reversal of glucocorticoid receptor activation (1982) Biochem. Biophys. Res. Comm., 195, pp. 20-27 | ||
| 504 | |a Kaufmann, S.H., Shaper, J.H., Binding of dexamethasone to rat liver nuclei in vivo and in vitro: Evidence for two distinct binding sites (1984) J. Steroid Biochem., 20, pp. 699-708 | ||
| 504 | |a Keefer, D.A., Stumpf, W.E., Sar, M., Topographical localization of estrogen concentrating cells in the rat spinal cord following3H-estradíol localization (1973) Proc. Soc. Exp. Biol. Med., 143, pp. 414-417 | ||
| 504 | |a Kovacic-Milivojevic, B., La Pointe, M.C., Reker, C.E., Vedeckis, W.V., Ribonucleic acid is a component of the oligomeric, transformed mouse AtT-20 cell glucocorticoid receptor (1985) Biochemistry, 24, pp. 7357-7366 | ||
| 504 | |a Luttge, W.G., Emadian, S.M., Further chemical differentiation of type I and type II adrenocorticosteroid receptors in mouse brain cytosol: Evidence for a new class of glucocorticoid receptor (1988) Brain Res., 435, pp. 41-50 | ||
| 504 | |a MacLusky, N.J., Clark, C.R., Shanabrough, M., Naftolin, F., Metabolism and binding of androgens in the spinal cord of the rat (1987) Brain Res., 422, pp. 83-91 | ||
| 504 | |a Magariños, A.M., Somoza, G., De Nicola, A.F., Glucocorticoid negative feedback and glucocorticoid receptors after hippocampectomy in rats (1987) Horm. Metab. Res., 19, pp. 105-109 | ||
| 504 | |a Magariños, A.M., Estivariz, F., Morano, M.I., De Nicola, A.F., Regulation of the central nervous system-pituitary adrenal axis in rats after neonatal treatment with monosodium glutamate (1988) Neuroendocrinology, 48, pp. 105-111 | ||
| 504 | |a Marver, D., Aldosterone action in target epithelia (1980) Vitam. Horm., 38, pp. 57-117 | ||
| 504 | |a McEwen, B. S. (1988). Steroid hormones in brain: Linking “nature” and “nurture.”Neurochem. Res. (in press); McEwen, B.S., Lambdin, L.T., Rainbow, T.C., De Nicola, A.F., Aldosterone effects on salt appetite in adrenalectomized rats (1986) Neuroendocrinology, 43, pp. 38-43 | ||
| 504 | |a McEwen, B.S., De Kloet, E.R., rostene, W., Adrenal steroid receptors and actions in the nervous system (1986) Physiol. Rev., 66, pp. 1121-1188 | ||
| 504 | |a Meaney, M.J., Aitken, D.H., (3H)-Dexamethasone binding in rat frontal cortex (1985) Brain Res., 328, pp. 176-182 | ||
| 504 | |a Meyer, J.S., Leveille, P.J., De Vellis, J., Gewrlach, J.L., McEwen, B.S., Evidence for glucocorticoid target cells in the rat optic nerve: Hormone binding and glycerolphosphate dehydrogenase induction (1982) J. Neurochem., 39, pp. 423-434 | ||
| 504 | |a Morrel, J.I., Wolinsky, T.D., Krieger, M.S., Pfaff, D.W., Autoradiographic identification of estradiol-concentrating cells in the spinal cord of the female rat (1982) Exp. Brain Res., 45, pp. 144-150 | ||
| 504 | |a Moses, D.F., Ortí, E., De Nicola, A.F., A comparison of the glucocorticoid receptor system in the spinal cord and hippocampus (1987) Brain Res., 408, pp. 118-124 | ||
| 504 | |a Moses, D.F., Gonzalez, S., Ortí, E., De Nicola, A.F., Heterogeneity and properties of transformation of corticosteroid receptors in spinal cord and hippocampus (1989) Brain Res., 481, pp. 317-324 | ||
| 504 | |a Ortí, E., Tornello, S., De Nicola, A.F., Dynamic aspects of glucocorticoid receptors in the spinal cord of the rat (1985) J. Neurochem., 45, pp. 1699-1707 | ||
| 504 | |a Ortí, E., Coirini, H., De Nicola, A.F., Properties and distribution of glucocorticoid binding sites in cytosol of the spinal cord (1985) Neuroendocrinology, 40, pp. 225-231 | ||
| 504 | |a Ortí, E., Magariños, A.M., De Nicola, A.F., Evidence of high affinity, stereoselective binding sites for (3H)-aldosterone in the spinal cord (1986) Neuroendocrinology, 43, pp. 404-409 | ||
| 504 | |a Ortí, E., Moses, D.F., Grillo, C., De Nicola, A.F., Glucocorticoid regulation of glycerolphosphate dehydrogenase and ornithine decarboxylase activities in the spinal cord of the rat (1987) J. Neurochem., 48, pp. 425-431 | ||
| 504 | |a Palkovits, M., Isolated removal of hypothalamic or other brain nuclei of the rat (1973) Brain Res., 59, pp. 449-450 | ||
| 504 | |a Reid, F.A., Gasc, J.-M., Stumpf, W.E., Sar, M., Androgen target cells in spinal cord, spinal ganglion and glycogen body of chick embryos (1981) Exp. Brain Res., 44, pp. 243-248 | ||
| 504 | |a Reul, J.M.H.M., De Kloet, E.P., Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation (1985) Endocrinology, 117, pp. 2502-2511 | ||
| 504 | |a Reul, J.M.H.M., van der Bosch, F.R., De Kloet, E.R., Relative occupation of type I and type II corticosteroid receptors in rat brain following stress and dexamethasone treatment: Functional implications (1987) J. Endocrinol., 115, pp. 459-467 | ||
| 504 | |a Rossini, G.P., RNAse effects on sedimentation and DNA-binding properties of dexamethasone-receptor complexes from HeLa-cell cytosol (1985) J. Steroid Biochem., 22, pp. 47-56 | ||
| 504 | |a Sar, M., Stumpf, W.E., Androgen concentration in motor neurons of cranial nerves and spinal cord (1977) Science, 197, pp. 77-79 | ||
| 504 | |a Schmidt, T.J., Litwack, G., Activation of the glucocorticoid-receptor complex (1982) Physiol. Rev., 62, pp. 1131-1192 | ||
| 504 | |a Simons, S.S., Martinez, H.M., Garcea, R.L., Baxter, J.D., Tomkins, G.M., Interactions of glucocorticoid-receptor complexes with acceptor sites (1976) J. Biol. Chem., 251, pp. 334-343 | ||
| 504 | |a Stumpf, W.E., Sar, M., Glucocorticosteroid and mineralocorticosteroid hormone target sites in the brain: Autoradiographic studies with corticosterone, aldosterone and dexamethasone (1979) Interaction Within the Brain-Pituitary-Adrenocortical System, pp. 137-147. , M. T., Jones, B., Gillham, M. F., Dallman, S., Chattopadhyay, Academic Press, London | ||
| 504 | |a Towle, A.C., Sze, P.Y., (3H)-Corticosterone binding in rat superior cervical ganglion (1982) Brain Res., 253, pp. 221-229 | ||
| 504 | |a Tymoczko, J.L., Phillips, M.H., The effects of ribonuclease on rat liver dexamethasone receptor: Increased affinity for deoxyribonucleic acid and alternated sedimentation profile (1983) Endocrinology, 112, pp. 142-149 | ||
| 504 | |a Warembourg, M., Steroid receptors in the brain: Topography and some functional implications (1985) Neurochem. Int., 7, pp. 941-952 | ||
| 504 | |a Weil, C., Characterization of glucocorticoid receptors in whole and cellular subfractions of embryonic chick spinal cord (1986) Dev. Brain Res., 27, pp. 167-173 | ||
| 504 | |a Wrange, O., Yu, Z.-Y., Mineralocorticoid receptors in rat kidney and hippocampus: Characterization and quantitation by isoelectric focusing (1983) Endocrinology, 113, pp. 243-250 | ||
| 504 | |a Yamamoto, K.R., Steroid receptor regulated transcription of specific genes and gene networks (1985) Annu. Rev. Genet., 19, pp. 209-252 | ||
| 520 | 3 | |a 1. Glucocorticoid hormones affect several functions of the spinal cord, such as synaptic transmission, biogenic amine content, lipid metabolism, and the activity of some enzymes (ornithine decarboxylase, glycerolphosphate dehydrogenase), indicating that this tissue is a target of adrenal hormones. 2. Corticosterone, the main glucocorticoid of the rat, is detected at all regional levels of the spinal cord, and cold stress increases this steroid, predominantly in the cervical regions. 3. Intracellular glucocorticoid receptors have been found in the spinal cord, with higher concentrations in the cervical and lumbar enlargements. Prima facie, these receptors presented biochemical, stereospecifical, and physicochemical properties similar to those of receptors found in other regions of the nervous system. The prevalent form in the spinal cord is the type II receptor, although type I is also present in small amounts. 4. The type II glucocorticoid receptor of the spinal cord shows an affinity lower (Kd 3.5 n M) than that of the hippocampal type II site (Kd 0.7 n M) when incubated with [3H]dexamethasone. This condition may impair the nuclear translocation of the spinal cord receptor. 5. Another peculiar property of spinal cord type II site is a greater affinity for DNA-cellulose binding than the hippocampal receptor during heat-induced transformation. Also, the spinal cord receptor shows resistance to the action of RNAse A, an enzyme which increases DNA-cellulose binding of the hippocampal receptor, indicating that both receptors may be structurally different. 6. Therefore, it is possible that a different subclass of type II, or "classical glucocorticoid receptor," is present in the spinal cord. This possibility makes the cord a useful system for studying diversity of glucocorticoid receptors of the nervous system, especially the relationship between receptor structure and function. © 1989 Plenum Publishing Corporation. |l eng | |
| 593 | |a Laboratorio de Bioquímica Neuroendócrina, Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina | ||
| 593 | |a Departamento de Bioquímica, Facultad de Medicina, Universidad de Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CENTRAL NERVOUS SYSTEM |
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a DEXAMETHASONE |
| 690 | 1 | 0 | |a HIPPOCAMPUS |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a STRESS |
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a DEXAMETHASONE |
| 690 | 1 | 0 | |a GLUCOCORTICOID RECEPTOR |
| 690 | 1 | 0 | |a RADIOISOTOPE |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a CENTRAL NERVOUS SYSTEM |
| 690 | 1 | 0 | |a HIPPOCAMPUS |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a RAT |
| 690 | 1 | 0 | |a RECEPTOR BINDING |
| 690 | 1 | 0 | |a REVIEW |
| 690 | 1 | 0 | |a SPINAL CORD |
| 690 | 1 | 0 | |a STRESS |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a BRAIN |
| 690 | 1 | 0 | |a CORTICOSTERONE |
| 690 | 1 | 0 | |a DEXAMETHASONE |
| 690 | 1 | 0 | |a GLUCOCORTICOIDS |
| 690 | 1 | 0 | |a RATS |
| 690 | 1 | 0 | |a RECEPTORS, GLUCOCORTICOID |
| 690 | 1 | 0 | |a RIBONUCLEASES |
| 690 | 1 | 0 | |a SPINAL CORD |
| 690 | 1 | 0 | |a STRESS |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 690 | 1 | 0 | |a SUPPORT, U.S. GOV'T, P.H.S. |
| 700 | 1 | |a Moses, D.F. | |
| 700 | 1 | |a González, S. | |
| 700 | 1 | |a Ortí, E. | |
| 773 | 0 | |d Kluwer Academic Publishers-Plenum Publishers, 1989 |g v. 9 |h pp. 179-192 |k n. 2 |p Cell Mol Neurobiol |x 02724340 |t Cellular and Molecular Neurobiology | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024339890&doi=10.1007%2fBF00713027&partnerID=40&md5=02c4a02fed47cd44ac4ecd94afdc81f8 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1007/BF00713027 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_02724340_v9_n2_p179_DeNicola |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02724340_v9_n2_p179_DeNicola |y Registro en la Biblioteca Digital |
| 961 | |a paper_02724340_v9_n2_p179_DeNicola |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 78887 | ||