Neonatal, placental, and umbilical cord blood parameters in pregnant women residing in areas with intensive pesticide application

In rural populations, the proximity to areas with intensive pesticide application represents a risk factor of xenobiotic exposure. Here, we investigated whether newborns born to mothers residing in an area with intensive pesticide application show alterations in placental and neonatal morphometric s...

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Autor principal: Quintana, M.M
Otros Autores: Vera, B., Magnarelli, G., Guiñazú, N., Rovedatti, M.G
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Lenguaje:Inglés
Publicado: Springer Verlag 2017
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024 7 |2 cas  |a Biomarkers; Pesticides 
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030 |a ESPLE 
100 1 |a Quintana, M.M. 
245 1 0 |a Neonatal, placental, and umbilical cord blood parameters in pregnant women residing in areas with intensive pesticide application 
260 |b Springer Verlag  |c 2017 
270 1 0 |m Rovedatti, M.G.; Laboratorio de Toxicología de Mezclas Químicas (LATOMEQ), Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 4to piso, Intendente Güiraldes 2160, Argentina; email: rovedattimg@gmail.com 
506 |2 openaire  |e Política editorial 
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520 3 |a In rural populations, the proximity to areas with intensive pesticide application represents a risk factor of xenobiotic exposure. Here, we investigated whether newborns born to mothers residing in an area with intensive pesticide application show alterations in placental and neonatal morphometric standards, umbilical cord blood (UCB) biochemical parameters, and/or biomarkers related to oxidative stress and oxidative damage. Samples were collected from 151 healthy pregnant women residing in a rural area (rural group; RG) during the pesticide spraying (SS) and nonspraying (NSS) seasons, as well as from women from an urban population (control group; CG), and grouped according to the delivery type (vaginal or cesarean). In the vaginal delivery group, the placental weight and placental index were higher in the RG groups than in the CG (p = 0.01), whereas in the cesarean delivery group, newborn weight was lower in the RG-SS group than in the CG. In the RG-SS group, UCB erythrocyte osmotic fragility and the DNA damage index (DI) were higher, and superoxide dismutase (SOD) activity was lower than in the RG-NSS group. Acetylcholinesterase and SOD activities were found to be inversely correlated with the DI. © 2017, Springer-Verlag GmbH Germany.  |l eng 
593 |a Facultad de Ciencias Médicas, Universidad Nacional del Comahue, Av. Luis Toschi y Los Arrayanes, Cipolletti, Río Negro 8324, Argentina 
593 |a Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue (CITAAC), CONICET, Universidad Nacional del Comahue, Buenos Aires 1400, Neuquén, 8300, Argentina 
593 |a Departamento de Ciencias del Ambiente, Facultad de Ciencias del Ambiente y la Salud, Universidad Nacional del Comahue, Buenos Aires 1400, Neuquén, 8300, Argentina 
593 |a Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes 2160, Buenos Aires, C1428EGA, Argentina 
593 |a Laboratorio de Toxicología de Mezclas Químicas (LATOMEQ), Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 4to piso, Intendente Güiraldes 2160, Buenos Aires, C1428EGA, Argentina 
690 1 0 |a DNA DAMAGE 
690 1 0 |a NEONATE PARAMETERS 
690 1 0 |a OSMOTIC FRAGILITY 
690 1 0 |a RESIDENTIAL EXPOSURE 
690 1 0 |a SUPEROXIDE DISMUTASE 
690 1 0 |a UMBILICAL CORD BLOOD 
690 1 0 |a BIOMARKER 
690 1 0 |a BLOOD 
690 1 0 |a DNA 
690 1 0 |a ENZYME 
690 1 0 |a ENZYME ACTIVITY 
690 1 0 |a HEALTH RISK 
690 1 0 |a NEONATE 
690 1 0 |a OXIDATIVE STRESS 
690 1 0 |a PESTICIDE APPLICATION 
690 1 0 |a PREGNANCY 
690 1 0 |a PUBLIC HEALTH 
690 1 0 |a RISK FACTOR 
690 1 0 |a RURAL AREA 
690 1 0 |a RURAL POPULATION 
690 1 0 |a URBAN POPULATION 
690 1 0 |a WOMENS HEALTH 
690 1 0 |a BIOLOGICAL MARKER 
690 1 0 |a PESTICIDE 
690 1 0 |a ADOLESCENT 
690 1 0 |a ADULT 
690 1 0 |a BLOOD 
690 1 0 |a CHEMISTRY 
690 1 0 |a FEMALE 
690 1 0 |a FETUS BLOOD 
690 1 0 |a HUMAN 
690 1 0 |a NEWBORN 
690 1 0 |a OXIDATIVE STRESS 
690 1 0 |a PREGNANCY 
690 1 0 |a RURAL POPULATION 
690 1 0 |a URBAN POPULATION 
690 1 0 |a VASCULARIZATION 
690 1 0 |a YOUNG ADULT 
690 1 0 |a ADOLESCENT 
690 1 0 |a ADULT 
690 1 0 |a BIOMARKERS 
690 1 0 |a FEMALE 
690 1 0 |a FETAL BLOOD 
690 1 0 |a HUMANS 
690 1 0 |a INFANT, NEWBORN 
690 1 0 |a OXIDATIVE STRESS 
690 1 0 |a PESTICIDES 
690 1 0 |a PREGNANCY 
690 1 0 |a RURAL POPULATION 
690 1 0 |a URBAN POPULATION 
690 1 0 |a YOUNG ADULT 
650 1 7 |2 spines  |a OSMOSIS 
650 1 7 |2 spines  |a PLACENTA 
650 1 7 |2 spines  |a PLACENTA 
651 4 |a ARGENTINA 
651 4 |a ARGENTINA 
700 1 |a Vera, B. 
700 1 |a Magnarelli, G. 
700 1 |a Guiñazú, N. 
700 1 |a Rovedatti, M.G. 
773 0 |d Springer Verlag, 2017  |g v. 24  |h pp. 20736-20746  |k n. 25  |p Environ. Sci. Pollut. Res.  |x 09441344  |t Environmental Science and Pollution Research 
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