Environmental pollution affects molecular and biochemical responses during gonadal maturation of Astyanax fasciatus (Teleostei: Characiformes: Characidae)
Endocrine disrupting compounds (EDCs) have the potential to alter fish reproduction at various levels of organization. The aim of this study was to assess the impact of a natural environment with heavily anthropogenic influence on the physiological processes involved in reproduction in the freshwate...
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Academic Press
2018
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| LEADER | 23277caa a22022577a 4500 | ||
|---|---|---|---|
| 001 | PAPER-17314 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230607131908.0 | ||
| 008 | 190410s2018 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-85030309074 | |
| 024 | 7 | |2 cas |a estradiol, 50-28-2; Biomarkers; Endocrine Disruptors; Estradiol; Vitellogenins; Water Pollutants, Chemical | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a EESAD | ||
| 100 | 1 | |a Tolussi, C.E. | |
| 245 | 1 | 0 | |a Environmental pollution affects molecular and biochemical responses during gonadal maturation of Astyanax fasciatus (Teleostei: Characiformes: Characidae) |
| 260 | |b Academic Press |c 2018 | ||
| 270 | 1 | 0 | |m Tolussi, C.E.; Laboratório de Metabolismo e Reprodução de Organismos Aquáticos, Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo. Rua do Matão, Trav.14, n° 321, Brazil; email: ctolussi@usp.br |
| 506 | |2 openaire |e Política editorial | ||
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| 520 | 3 | |a Endocrine disrupting compounds (EDCs) have the potential to alter fish reproduction at various levels of organization. The aim of this study was to assess the impact of a natural environment with heavily anthropogenic influence on the physiological processes involved in reproduction in the freshwater fish lambari (Astyanax fasciatus) using different biomarkers. Adult males and females were collected in different seasons from two distinct sites in the same watershed: Ponte Nova Reservoir (PN) considered a pristine or small anthropogenic influence reference point; and Billings Reservoir (Bil), subjected to a large anthropogenic impact. Biological indices, such as hepatosomatic index and gonadosomatic index (GSI), gonadal histomorphology, fecundity, and biomarkers such as plasma levels of estradiol (E2) as well as hepatic gene expression of its alfa nuclear receptor (ERα), were analyzed. Hepatic vitellogenin (VTG) gene expression was evaluated in both sexes, as an indicator of xenoestrogen exposure. Females collected at PN presented a typical annual variation reflected in GSI, whereas for those sampled at Bil the index did not change through the seasons. The higher concentration of E2 in males collected at Bil during spring/2013, together with the detection of VTG gene expression, suggest the presence of EDCs in the water. These EDCs may have also influenced fecundity of females from Bil, which was higher during winter and spring/2013. Gene expression of ERα and ovarian morphology did not differ between fish from both sites. Water conditions from Bil reservoir impacted by anthropic activity clearly interfered mainly with biomarkers of biological effect such as plasma E2 levels and absolute and relative fecundity, but also altered biomarkers of exposure as VTG gene expression. These facts support the notion that waterborne EDCs are capable of causing estrogenic activity in A. fasciatus. © 2017 Elsevier Inc. |l eng | |
| 536 | |a Detalles de la financiación: Fundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP, 2014/01866-4, 12/50371-2, 2011/15453-5 | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires, UBA | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, 2013/50480-9 | ||
| 536 | |a Detalles de la financiación: This work was supported by FAPESP ( Fundação de Amparo à Pesquisa do Estado de São Paulo ) [Research Grant: 12/50371-2 , a Ph.D. scholarship: 2011/15453-5 and a scholarship stage through the International Research Project: 2014/01866-4 ] FAPESP-CONICET ( Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina ) [ 2013/50480-9 ]. We thank the Laboratorio de Ecotoxicología Acuática at Universidad de Buenos Aires, Argentina; and Contaminant Biogeochemistry and Environmental Toxicology group of Common Wealth Scientific and Industrial Research Organization at Adelaide, Australia. The authors also thank the fishermen (Evaldo Bizarrias and Milton Nunes de Santana), and the LAMEROA team for their help with sampling and IB/USP for providing logistics and facilities for the study. | ||
| 593 | |a Laboratório de Metabolismo e Reprodução de Organismos Aquáticos, Departamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo. Rua do Matão, Trav.14, n° 321, São Paulo, SP 05508-090, Brazil | ||
| 593 | |a Environmental Contaminant Mitigation and Technologies Program, CSIRO Land and Water, Private Bag No. 2, Glen Osmond, SA 5064, Australia | ||
| 593 | |a Departamento de Biologia e Zootecnia, Universidade Estadual Paulista Júlio de Mesquita Filho, Campus de Ilha Solteira, Rua Monção, n°226, Ilha Solteira, 15385-000, Brazil | ||
| 593 | |a Laboratorio de Ecotoxicología Acuática, Departamento de Biodiversidad y Biología Experimental, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires & IBBEA, CONICET-UBA, Ciudad Universitaria (C1428EHA), Buenos Aires, Argentina | ||
| 593 | |a Centro de Aquicultura (CAUNESP). Universidade Estadual Paulista Júlio de Mesquita Filho, V. Acesso Prof. Paulo Donato Castelane s/n, Jaboticabal, SP 14884-900, Brazil | ||
| 690 | 1 | 0 | |a ANTHROPOGENIC IMPACT |
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| 700 | 1 | |a Gomes, A.D.O. | |
| 700 | 1 | |a Kumar, A. | |
| 700 | 1 | |a Ribeiro, C.S. | |
| 700 | 1 | |a Nostro, F.L.L. | |
| 700 | 1 | |a Bain, P.A. | |
| 700 | 1 | |a de Souza, G.B. | |
| 700 | 1 | |a Cuña, R.D. | |
| 700 | 1 | |a Honji, R.M. | |
| 700 | 1 | |a Moreira, R.G. | |
| 773 | 0 | |d Academic Press, 2018 |g v. 147 |h pp. 926-934 |p Ecotoxicol. Environ. Saf. |x 01476513 |w (AR-BaUEN)CENRE-4483 |t Ecotoxicology and Environmental Safety | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/j.ecoenv.2017.09.056 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01476513_v147_n_p926_Tolussi |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01476513_v147_n_p926_Tolussi |y Registro en la Biblioteca Digital |
| 961 | |a paper_01476513_v147_n_p926_Tolussi |b paper |c PE | ||
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| 963 | |a VARI | ||
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