What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?

Cytogenetic studies in Cebus spp. have highlighted a peculiar genomic feature: the presence of conspicuous regions of extracentromeric heterochromatin distributed throughout the karyotype. This study investigates the distribution, variability and composition of heterochromatin and their possible imp...

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Autor principal: Nieves, M.
Otros Autores: Fantini, L., Mudry, M.D
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Publicado: Oxford University Press 2018
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100 1 |a Nieves, M. 
245 1 5 |a What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)? 
260 |b Oxford University Press  |c 2018 
270 1 0 |m Nieves, M.; Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Ecologia, Genetica y Evolucion, Grupo de Investigación en Biología Evolutiva (GIBE), Ciudad Universitaria, Pabellón 2, 4o piso, Laboratorios 43 y 46, Argentina; email: mariela.nieves5@gmail.com 
506 |2 openaire  |e Política editorial 
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520 3 |a Cytogenetic studies in Cebus spp. have highlighted a peculiar genomic feature: the presence of conspicuous regions of extracentromeric heterochromatin distributed throughout the karyotype. This study investigates the distribution, variability and composition of heterochromatin and their possible implications for genome dynamics. We performed a molecular cytogenetic analysis in 253 individuals from seven of the 12 currently recognized species. The proportion of heterochromatin was related to genome size and ranked, from smallest to largest, from C. xanthosternos to C. albifrons. Interspecies comparative genome hybridization analyses suggested that the differences among species are not related to heterochromatin content but to changes in the Y chromosome. The pattern revealed by DAPI/CMA3 staining showed that Cebus heterochromatic DNA has a GC-rich composition. The distribution frequencies of heteromorphisms and polymorphisms were not randomly distributed, because a distinguishable pattern could be recognized for each group. Cebus cay and C. nigritus had a higher level of heterochromatin variability than previously reported. In conclusion, the wide variability among species of the genus Cebus is mostly due to the repetitive DNA fraction of its genome. © 2017 The Linnean Society of London, Biological Journal of the Linnean Society.  |l eng 
536 |a Detalles de la financiación: Secretaría de Ciencia y Tecnología, Gobierno de la Provincia de Córdoba, UBACyT 
536 |a Detalles de la financiación: Universidad de Buenos Aires, X154 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, PIP 0744 
536 |a Detalles de la financiación: This study was supported by the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET; Project PIP 0744) and grants from the Secretaría de Ciencia y Tecnología (UBACyT) of the Universidad de Buenos Aires (Project X154) to M.D.M. We thank all the zoological institutions, researchers and collaborators from different localities for issuing the permits required for access to sampling sites and biological materials and for sample transportation. We especially acknowledge the assistance of veterinarians who helped us to capture and handle monkeys and Professor Gregory and the staff of the Laboratory of Genomic Diversity, University of Guelph, Ontario, Canada, for C-value measurements. Biological sampling was conducted in compliance with the guidelines for the care and manipulation of animals established by the Ethical Committee of the Argentine Society for Mammalian Studies (SAREM). Finally we thank five reviewers for their helpful comments. 
593 |a Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Ecologia, Genetica y Evolucion, Grupo de Investigación en Biología Evolutiva (GIBE), Ciudad Universitaria, Pabellón 2, 4o piso, Laboratorios 43 y 46, Buenos Aires, C1428EGA, Argentina 
593 |a Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-UBA, Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA), Ciudad Universitaria, Pabellón 2, 4o piso, Buenos Aires, C1428EGA, Argentina 
593 |a Universidad Nacional A. Jauretche, Buenos Aires, Argentina 
690 1 0 |a CEBUS 
690 1 0 |a GC CONTENT 
690 1 0 |a GENOME DYNAMICS 
690 1 0 |a GENOME SIZE 
690 1 0 |a HETEROCHROMATIN 
690 1 0 |a ICGH 
690 1 0 |a MOLECULAR CYTOGENETICS 
690 1 0 |a NEOTROPICAL PRIMATES 
690 1 0 |a POLYMORPHISMS 
690 1 0 |a CHROMOSOME 
690 1 0 |a CYTOGENETICS 
690 1 0 |a GENOME 
690 1 0 |a GENOMICS 
690 1 0 |a HYBRIDIZATION 
690 1 0 |a MOLECULAR ANALYSIS 
690 1 0 |a POLYMORPHISM 
690 1 0 |a PRIMATE 
690 1 0 |a CEBUS 
690 1 0 |a CEBUS ALBIFRONS 
690 1 0 |a CEBUS XANTHOSTERNOS 
690 1 0 |a PLATYRRHINI 
650 1 7 |2 spines  |a PRIMATES 
700 1 |a Fantini, L. 
700 1 |a Mudry, M.D. 
773 0 |d Oxford University Press, 2018  |g v. 123  |h pp. 113-124  |k n. 1  |p Biol. J. Linn. Soc.  |x 00244066  |w (AR-BaUEN)CENRE-3388  |t Biological Journal of the Linnean Society 
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