Guanosine diphosphate d-glucose glucohydrolase
A new enzyme has been found in yeast, which catalyzes the hydrolysis of guanosine diphosphate glucose to guanosine diphosphate and glucose. The enzyme was purified about 130-fold and its kinetic properties were studied. The enzymic activity seems to be strictly specific for guanosine diphosphate glu...
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| Otros Autores: | , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1966
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 04266caa a22006617a 4500 | ||
|---|---|---|---|
| 001 | PAPER-1669 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203101.0 | ||
| 008 | 190411s1966 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0014028957 | |
| 024 | 7 | |2 cas |a glucose, 50-99-7, 84778-64-3; glycosidase, 9032-92-2; magnesium, 7439-95-4; mannose, 31103-86-3, 3458-28-4; Glucose, 50-99-7; Glycoside Hydrolases, EC 3.2.1.; Guanine Nucleotides; Magnesium, 7439-95-4; Mannose, 31103-86-3 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a ABBIA | ||
| 100 | 1 | |a Sonnino, S. | |
| 245 | 1 | 0 | |a Guanosine diphosphate d-glucose glucohydrolase |
| 260 | |c 1966 | ||
| 270 | 1 | 0 | |m Sonnino, S.; Instituto de Investigaciones Bioquímicas Fundacion Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490 Buenos Aires (28), Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a A new enzyme has been found in yeast, which catalyzes the hydrolysis of guanosine diphosphate glucose to guanosine diphosphate and glucose. The enzyme was purified about 130-fold and its kinetic properties were studied. The enzymic activity seems to be strictly specific for guanosine diphosphate glucose, with a Km of 0.23 mm. The enzyme is active over a wide range of pH values, from 5 to 9. Guanosine diphosphate inhibits competitively and Mg++ partially relieves the inhibition. The enzyme appears to exist in soluble form in the cytoplasm. The possible significance of guanosine diphosphate glucose glucohydrolase and of sugar nucleotide phosphorylase in the control of the intracellular concentration of guanosine diphosphate glucose and guanosine diphosphate mannose is discussed. © 1966. |l eng | |
| 536 | |a Detalles de la financiación: 8ervice | ||
| 536 | |a Detalles de la financiación: Foundation for the National Institutes of Health | ||
| 536 | |a Detalles de la financiación: Rockefeller Foundation | ||
| 536 | |a Detalles de la financiación: 1 Dedicated to Luis F. Leloir on the occasion of his sixtieth birthday. ? This investigation was supported in part 1)~ research grant GM 03-l-12 from the National Institutes Health, Llnited States Public Health 8ervice; by the Consejo National de Investiga-ciones Cientificas y TBcnicas (Reptiblica Argentina,); and by the Rockefeller Foundation. 3 Career investigator of the Consejo National de Investigaciones Cientificas y Tficnicns (R,e-ptihlica Argentina). 4 It is generally acknowledged catalyzed by pyrophosphorylases ceeds toward the synthesis under conditions prevailing | ||
| 593 | |a Instituto de Investigaciones Bioquímicas Fundacion Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490 Buenos Aires (28), Argentina | ||
| 690 | 1 | 0 | |a GLUCOSE |
| 690 | 1 | 0 | |a GLYCOSIDASE |
| 690 | 1 | 0 | |a GUANINE NUCLEOTIDE |
| 690 | 1 | 0 | |a MAGNESIUM |
| 690 | 1 | 0 | |a MANNOSE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CHROMATOGRAPHY |
| 690 | 1 | 0 | |a ELECTROPHORESIS |
| 690 | 1 | 0 | |a ENZYMOLOGY |
| 690 | 1 | 0 | |a GEL CHROMATOGRAPHY |
| 690 | 1 | 0 | |a KINETICS |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a SACCHAROMYCES |
| 690 | 1 | 0 | |a CHROMATOGRAPHY |
| 690 | 1 | 0 | |a CHROMATOGRAPHY, GEL |
| 690 | 1 | 0 | |a ELECTROPHORESIS |
| 690 | 1 | 0 | |a GLUCOSE |
| 690 | 1 | 0 | |a GLYCOSIDE HYDROLASES |
| 690 | 1 | 0 | |a GUANINE NUCLEOTIDES |
| 690 | 1 | 0 | |a KINETICS |
| 690 | 1 | 0 | |a MAGNESIUM |
| 690 | 1 | 0 | |a MANNOSE |
| 690 | 1 | 0 | |a SACCHAROMYCES |
| 700 | 1 | |a Carminatti, H. | |
| 700 | 1 | |a Cabib, E. | |
| 773 | 0 | |d 1966 |g v. 116 |h pp. 26-33 |k n. C |p Arch. Biochem. Biophys. |x 00039861 |w (AR-BaUEN)CENRE-1377 |t Archives of Biochemistry and Biophysics | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-0014028957&doi=10.1016%2f0003-9861%2866%2990007-5&partnerID=40&md5=4429d5db8bb0ac550366511e7a21d863 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/0003-9861(66)90007-5 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00039861_v116_nC_p26_Sonnino |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00039861_v116_nC_p26_Sonnino |y Registro en la Biblioteca Digital |
| 961 | |a paper_00039861_v116_nC_p26_Sonnino |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 62622 | ||