The role of GABAA in the expression of updated information through the reconsolidation process in humans
Consolidated memory can be again destabilized by the presentation of a memory cue (reminder) of the previously acquired information. During this process of labilization/restabilization memory traces can be either impaired, strengthened or updated in content. Here, we study if a consolidated memory c...
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| Formato: | Capítulo de libro |
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Academic Press Inc.
2017
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| 003 | AR-BaUEN | ||
| 005 | 20230518204530.0 | ||
| 008 | 190410s2017 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-85016627366 | |
| 024 | 7 | |2 cas |a 4 aminobutyric acid, 28805-76-7, 56-12-2; clonazepam, 1622-61-3; Clonazepam; GABA Modulators | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a NLMEF | ||
| 100 | 1 | |a Fernández, R.S. | |
| 245 | 1 | 4 | |a The role of GABAA in the expression of updated information through the reconsolidation process in humans |
| 260 | |b Academic Press Inc. |c 2017 | ||
| 270 | 1 | 0 | |m Forcato, C.; Unidad Ejecutora de Estudios de Neurociencias y Sistemas Complejos, Consejo Nacional de Investigaciones Científicas y Tecnológicas, Universidad Nacional Arturo Jauretche, Hospital de Alta Complejidad en Red El Cruce “Néstor Kirchner”Argentina; email: cecilia.forcato@gmail.com |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Alvares, L.D.O., Crestani, A.P., Cassini, L.F., Haubrich, J., Santana, F., Quillfeldt, J.A., Reactivation enables memory updating, precision-keeping and strengthening: Exploring the possible biological roles of reconsolidation (2013) Neuroscience, 244, pp. 42-48 | ||
| 504 | |a Anderson, M.C., Rethinking interference theory: Executive control and the mechanisms of forgetting (2003) Journal of Memory and Language, 49 (4), pp. 415-445 | ||
| 504 | |a Anderson, M.C., Bjork, R.A., Bjork, E.L., Remembering can cause forgetting: Retrieval dynamics in long-term memory (1994) Journal of Experimental Psychology. Learning, Memory, and Cognition, 20 (5), pp. 1063-1087 | ||
| 504 | |a Anderson, M.C., Ochsner, K.N., Kuhl, B., Cooper, J., Robertson, E., Gabrieli, S.W., Gabrieli, J.D., Neural systems underlying the suppression of unwanted memories (2004) Science, 303 (5655), pp. 232-235 | ||
| 504 | |a Bjork, E.L., Bjork, R.A., Continuing influences of to-be-forgotten information (1996) Consciousness and Cognition, 5 (1), pp. 176-196 | ||
| 504 | |a Bouton, M.E., Context and behavioral processes in extinction (2004) Learning & Memory, 11 (5), pp. 485-494 | ||
| 504 | |a Bustos, S.G., Maldonado, H., Molina, V.A., Midazolam disrupts fear memory reconsolidation (2006) Neuroscience, 139 (3), pp. 831-842 | ||
| 504 | |a Byrne, J.H., Concise learning and memory: The editor's selection (2010), https://books.google.com.ar/books?hl=es&lr=&id=4jhdCt1S3zcC&oi=fnd&pg=PP2&dq=byrne+concise+learning+and+memory&ots=VpwqPsTLpN&sig=X-eaoa3PLE8-Xa7B3cOSZMPkl-A, Academic Press. Retrieved from <>; Carbo Tano, M., Molina, V.A., Maldonado, H., Pedreira, M.E., Memory consolidation and reconsolidation in an invertebrate model: The role of the GABAergic system (2009) Neuroscience, 158 (2), pp. 387-401 | ||
| 504 | |a Chan, J.C., LaPaglia, J.A., Impairing existing declarative memory in humans by disrupting reconsolidation (2013) Proceedings of the National Academy of Sciences, 110 (23), pp. 9309-9313 | ||
| 504 | |a Chapouthier, G., Venault, P., GABA-A receptor complex and memory processes (2002) Current Topics in Medicinal Chemistry, 2 (8), pp. 841-851 | ||
| 504 | |a Corcoran, K.A., Maren, S., Hippocampal inactivation disrupts contextual retrieval of fear memory after extinction (2001) The Journal of Neuroscience, 21 (5), pp. 1720-1726 | ||
| 504 | |a Dudai, Y., The restless engram: Consolidations never end (2012) Annual Review of Neuroscience, 35, pp. 227-247 | ||
| 504 | |a Erdö, S.L., Bowery, N.G., GABAergic mechanisms in the mammalian periphery (1986), Raven Press (ID); Exton-McGuinness, M.T., Lee, J.L., Reichelt, A.C., Updating memories—The role of prediction errors in memory reconsolidation (2015) Behavioural Brain Research, 278, pp. 375-384 | ||
| 504 | |a Fernández, R.S., Bavassi, L., Forcato, C., Pedreira, M.E., The dynamic nature of the reconsolidation process and its boundary conditions: Evidence based on human tests (2016) Neurobiology of Learning and Memory, 130, pp. 202-212 | ||
| 504 | |a Fernández, R.S., Bavassi, L., Kaczer, L., Forcato, C., Pedreira, M.E., Interference conditions of the reconsolidation process in humans: The role of valence and different memory systems (2016) Frontiers in Human Neuroscience, 10 | ||
| 504 | |a Fernández, R.S., Boccia, M.M., Pedreira, M.E., The fate of memory: Reconsolidation and the case of Prediction Error (2016), http://www.sciencedirect.com/science/article/pii/S0149763415301639, Neuroscience & Biobehavioral Reviews. Retrieved from <>; Finnie, P.S.B., Nader, K., The role of metaplasticity mechanisms in regulating memory destabilization and reconsolidation (2012) Neuroscience and Biobehavioral Reviews, 36 (7), pp. 1667-1707 | ||
| 504 | |a Forcato, C., Argibay, P.F., Pedreira, M.E., Maldonado, H., Human reconsolidation does not always occur when a memory is retrieved: The relevance of the reminder structure (2009) Neurobiology of Learning and Memory, 91 (1), pp. 50-57 | ||
| 504 | |a Forcato, C., Burgos, V.L., Argibay, P.F., Molina, V.A., Pedreira, M.E., Maldonado, H., Reconsolidation of declarative memory in humans (2007) Learning & Memory, 14 (4), pp. 295-303. , (Cold Spring Harbor, N.Y.) | ||
| 504 | |a Forcato, C., Fernandez, R.S., Pedreira, M.E., The role and dynamic of strengthening in the reconsolidation process in a human declarative memory: What decides the fate of recent and older memories? (2013) PloS One, 8 (4), p. e61688 | ||
| 504 | |a Forcato, C., Rodríguez, M.L.C., Pedreira, M.E., Repeated labilization-reconsolidation processes strengthen declarative memory in humans (2011) PloS One, 6 (8), p. e23305 | ||
| 504 | |a Forcato, C., Rodríguez, M.L.C., Pedreira, M.E., Maldonado, H., Reconsolidation in humans opens up declarative memory to the entrance of new information (2010) Neurobiology of Learning and Memory, 93 (1), pp. 77-84 | ||
| 504 | |a Fukushima, H., Zhang, Y., Archbold, G., Ishikawa, R., Nader, K., Kida, S., Enhancement of fear memory by retrieval through reconsolidation (2014) Elife, 3, p. e02736 | ||
| 504 | |a Golding, J.M., MacLeod, C.M., Intentional forgetting: Interdisciplinary approaches (2013), https://books.google.com.ar/books?hl=es&lr=&id=3B0sXCQTcmEC&oi=fnd&pg=PP1&dq=macleod+directed+forgetting&ots=c2ytuEIGU2&sig=NYr9icEXD6COlLcTM3_FAHC0fzw, Psychology Press Retrieved from: <>; Holland, P.C., Gallagher, M., Different roles for amygdala central nucleus and substantia innominata in the surprise-induced enhancement of learning (2006) The Journal of Neuroscience, 26 (14), pp. 3791-3797 | ||
| 504 | |a Harris, J.A., Westbrook, R.F., Evidence that GABA transmission mediates context-specific extinction of learned fear (1998) Psychopharmacology, 140 (1), pp. 105-115 | ||
| 504 | |a Hupbach, A., The specific outcomes of reactivation-induced memory changes depend on the degree of competition between old and new information (2011), http://pubmedcentralcanada.ca/pmcc/articles/PMC3124834/, Frontiers in Behavioral Neuroscience, 5. Retrieved from <>; Hupbach, A., Gomez, R., Hardt, O., Nadel, L., Reconsolidation of episodic memories: A subtle reminder triggers integration of new information (2007) Learning & Memory, 14 (1-2), pp. 47-53. , (Cold Spring Harbor, N.Y.) | ||
| 504 | |a Hupbach, A., Sahakyan, L., Additional boundary condition for list-method directed forgetting: The effect of presentation format (2014) Journal of Experimental Psychology: Learning, Memory, and Cognition, 40 (2), p. 596 | ||
| 504 | |a Jacques, P.L.S., Olm, C., Schacter, D.L., Neural mechanisms of reactivation-induced updating that enhance and distort memory (2013) Proceedings of the National Academy of Sciences, 110 (49), pp. 19671-19678 | ||
| 504 | |a Kim, J.H., Richardson, R., A developmental dissociation of context and GABA effects on extinguished fear in rats (2007) Behavioral Neuroscience, 121 (1), p. 131 | ||
| 504 | |a Lee, J.L., Reconsolidation: Maintaining memory relevance (2009) Trends in Neurosciences, 32 (8), pp. 413-420 | ||
| 504 | |a Macleod, C.M., The item and list methods of directed forgetting: Test differences and the role of demand characteristics (1999) Psychonomic Bulletin & Review, 6 (1), pp. 123-129 | ||
| 504 | |a McGaugh, J.L., Memory – A century of consolidation (2000) Science (New York, N.Y.), 287 (5451), pp. 248-251 | ||
| 504 | |a Myers, K.M., Davis, M., Behavioral and neural analysis of extinction (2002) Neuron, 36 (4), pp. 567-584 | ||
| 504 | |a Nader, K., Schafe, G.E., Le Doux, J.E., Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval (2000) Nature, 406 (6797), pp. 722-726 | ||
| 504 | |a Paredes, R.G., Agmo, A., GABA and behavior: The role of receptor subtypes (1992) Neuroscience & Biobehavioral Reviews, 16 (2), pp. 145-170 | ||
| 504 | |a Pearce, J.M., Bouton, M.E., Theories of associative learning in animals (2001) Annual Review of Psychology, 52 (1), pp. 111-139 | ||
| 504 | |a Pedreira, M.E., Maldonado, H., Protein synthesis subserves reconsolidation or extinction depending on reminder duration (2003) Neuron, 38 (6), pp. 863-869 | ||
| 504 | |a Rescorla, R.A., Wagner, A.R., A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement (1972) Classical Conditioning II: Current Research and Theory, pp. 64-99 | ||
| 504 | |a Rizio, A.A., Dennis, N.A., The neural correlates of cognitive control: Successful remembering and intentional forgetting (2013) Journal of Cognitive Neuroscience, 25 (2), pp. 297-312 | ||
| 504 | |a Rodríguez, M.L.C., Campos, J., Forcato, C., Leiguarda, R., Maldonado, H., Molina, V.A., Pedreira, M.E., Enhancing a declarative memory in humans: The effect of clonazepam on reconsolidation (2013) Neuropharmacology, 64, pp. 432-442 | ||
| 504 | |a Schultz, W., Dickinson, A., Neuronal coding of prediction errors (2000) Annual Review of Neuroscience, 23 (1), pp. 473-500 | ||
| 504 | |a Tano, M.C., Molina, V.A., Pedreira, M.E., The involvement of the GABAergic system in the formation and expression of the extinction memory in the crab Neohelice granulata (2013) European Journal of Neuroscience, 38 (9), pp. 3302-3313 | ||
| 504 | |a Zhang, S., Cranney, J., The role of GABA and anxiety in the reconsolidation of conditioned fear (2008) Behavioral Neuroscience, 122 (6), p. 1295 | ||
| 520 | 3 | |a Consolidated memory can be again destabilized by the presentation of a memory cue (reminder) of the previously acquired information. During this process of labilization/restabilization memory traces can be either impaired, strengthened or updated in content. Here, we study if a consolidated memory can be updated by linking one original cue to two different outcomes and whether this process was modulated by the GABAergic system. To aim that, we designed two experiments carried out in three consecutive days. All participants learned a list of non-sense syllable pairs on day 1. On day 2 the new information was introduced after the reminder or no-reminder presentation. Participants were tested on day 3 for the updated or original list (Exp. 1). In Exp. 2 we tested whether this new information was incorporated by an inhibitory process mediated by the GABAergic system. For that, participants retrieved the original information before being taken Clonazepam 0.25 mg (GABAA agonist) or Placebo pill. We found that the groups that received the reminder correctly recalled the old and new information. However, the no reminder groups only correctly recalled the original information. Furthermore, when testing occurred in the presence of Clonazepam, the group that received the reminder plus the new information showed an impaired original memory performance compared to the group that received only Clonazepam (without reminder) or the reminder plus Placebo pill. These results show that new information can be added to a reactivated declarative memory in humans by linking one cue to two different outcomes. Furthermore, we shed light on the mechanisms of memory updating being the GABAergic system involved in the modulation of the old and new information expression. © 2017 Elsevier Inc. |l eng | |
| 536 | |a Detalles de la financiación: Fondo para la Investigación Científica y Tecnológica, PICT 2013-0412, PICT2010-0391 | ||
| 536 | |a Detalles de la financiación: We thank Carbone J. for assistance in preparation of the manuscript. This work was supported by FonCyT (grant PICT2010-0391 and PICT 2013-0412). | ||
| 593 | |a Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Argentina | ||
| 593 | |a CONICET-Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE), Buenos Aires, Argentina | ||
| 593 | |a Unidad Ejecutora de Estudios de Neurociencias y Sistemas Complejos, Consejo Nacional de Investigaciones Científicas y Tecnológicas, Universidad Nacional Arturo Jauretche, Hospital de Alta Complejidad en Red El Cruce “Néstor Kirchner”, Florencio Varela, Argentina | ||
| 593 | |a Departamento de Neurología Cognitiva, Instituto de Investigaciones Neurológicas Raúl Carrea, Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a BENZODIAZEPINE |
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| 690 | 1 | 0 | |a RECONSOLIDATION |
| 690 | 1 | 0 | |a 4 AMINOBUTYRIC ACID |
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| 700 | 1 | |a Moyano, M.D. | |
| 700 | 1 | |a Radloff, M. | |
| 700 | 1 | |a Campos, J. | |
| 700 | 1 | |a Carbó-Tano, M. | |
| 700 | 1 | |a Allegri, R.F. | |
| 700 | 1 | |a Pedreira, M.E. | |
| 700 | 1 | |a Forcato, C. | |
| 773 | 0 | |d Academic Press Inc., 2017 |g v. 142 |h pp. 146-153 |p Neurobiol. Learn. Mem. |x 10747427 |w (AR-BaUEN)CENRE-6249 |t Neurobiology of Learning and Memory | |
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