Polyamines modulate streptomycin-induced mistranslation in Escherichia coli

The effects of intracellular levels of polyamines on both the in vivo inhibition of protein synthesis and the decrease of translation accuracy induced by streptomycin have been studied in polyamine-auxotrophic strains of Escherichia coli infected with the MS2 bacteriophage. The amount of viral coat...

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Autor principal: Nastri, H.G
Otros Autores: Fastame, I.G, Algranati, I.D
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1993
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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024 7 |2 scopus  |a 2-s2.0-0027763343 
024 7 |2 cas  |a Bacterial Proteins; Methionine, 63-68-3; Polyamines; Streptomycin, 57-92-1 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a BBGSD 
100 1 |a Nastri, H.G. 
245 1 0 |a Polyamines modulate streptomycin-induced mistranslation in Escherichia coli 
260 |c 1993 
270 1 0 |m Algranati, I.D.; Instituto de Investigaciones Bioquímicas 'Fundación Campomar', Facultad de Ciencias Exactas y Naturales, University of Buenos Aires, A. Machado 151, 1405 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Algranati, Goldemberg, (1977) Trends Biochem. Sci., 2, pp. 272-274 
504 |a Atkins, Lewis, Anderson, Gesteland, (1975) J. Biol. Chem., 250, pp. 5688-5695 
504 |a Höltä, Hovi, (1985) Eur. J. Biochem., 152, pp. 229-237 
504 |a Takeda, Igarashi, (1972) J. Bacteriol., 111, pp. 1-6 
504 |a Barbiroli, Mezzetti, Moruzzi, (1989) The Physiology of Polyamines, 1, pp. 125-132. , 2nd Edn., U. Bachrach, Y.M. Heimer, CRC Press, Boca Raton 
504 |a Hunter, Farrell, Jackson, Hunt, (1977) Eur. J. Biochem., 75, pp. 149-157 
504 |a Echandi, Algranati, (1975) Biochem. Biophys. Res. Commun., 67, pp. 1185-1191 
504 |a McMurry, Algranati, (1986) Eur. J. Biochem., 155, pp. 383-390 
504 |a Igarashi, Kashiwagi, Kishida, Kakegawa, Hirose, (1981) Eur. J. Biochem., 114, pp. 127-131 
504 |a Igarashi, Kishida, Kashiwagi, Tatokoro, Kakegawa, Hirose, (1981) Eur. J. Biochem., 113, pp. 587-593 
504 |a Goldemberg, Algranati, (1981) Eur. J. Biochem., 111, pp. 251-255 
504 |a Algranati, Goldemberg, (1989) The Physiology of Polyamines, 1, pp. 143-156. , 2nd Edn., U. Bachrach, Y.M. Heimer, CRC Press, Boca Raton 
504 |a Goldemberg, Fernández-Velasco, Algranati, (1982) FEBS Lett., 142, pp. 275-279 
504 |a Cataldi, Algranati, (1986) Biochem. J., 234, pp. 617-622 
504 |a Nastri, Algranati, (1988) Biochim. Biophys. Acta, 949, pp. 65-70 
504 |a Thomas, (1978) Techniques in Protein and Enzyme Biochemistry, 106 B, pp. 1-22. , 2nd Edn., H.L. Kornberg et al., Elsevier/North-Holland, New York 
504 |a O'Farrell, (1975) J. Biol. Chem., 250, pp. 4007-4021 
504 |a O'Farrell, Goodman, O'Farrell, (1977) Cell, 12, pp. 1133-1142 
504 |a Goldemberg, Algranati, (1981) Med. Biol., 59, pp. 360-367 
504 |a Fromageot, Zinder, (1968) Proc. Natl. Acad. Sci. USA, 61, pp. 184-191. , 2nd Edn 
504 |a Beremand, Blumenthal, (1979) Cell, 18, pp. 257-266 
504 |a Khazaie, Buchanan, Rosenberger, (1984) Eur. J. Biochem., 144, pp. 485-489 
504 |a Parker, Johnston, Borgia, (1980) Mol. Gen. Genet., 180, pp. 275-281 
504 |a Parker, Johnston, Borgia, Holtz, Remant, Fiers, (1983) J. Biol. Chem., 258, pp. 10007-10012 
504 |a Johnston, Parker, (1985) J. Mol. Biol., 181, pp. 313-315 
504 |a Domingo, Sabo, Taniguchi, Weissmann, (1978) Cell, 13, pp. 735-744 
504 |a Davis, Chen, Tai, (1986) Proc. Natl. Acad. Sci. USA, 83, pp. 6164-6168. , 2nd Edn 
504 |a Davis, (1987) Microbiol. Rev., 51, pp. 341-350 
520 3 |a The effects of intracellular levels of polyamines on both the in vivo inhibition of protein synthesis and the decrease of translation accuracy induced by streptomycin have been studied in polyamine-auxotrophic strains of Escherichia coli infected with the MS2 bacteriophage. The amount of viral coat protein formed was strongly reduced upon addition of increasing concentrations of streptomycin to polyamine-supplemented bacteria. In contrast, the antibiotic almost did not inhibit coat protein synthesis in polyamine-starved cells. The increase of mistranslation frequency elicited by streptomycin was only observed in bacteria grown with putrescine. In these cells several coat protein-satellites were detected after two-dimensional gel electrophoresis. These proteins, more basic than the normal MS2 coat protein, contain multiple substitutions of lysine for asparagine. © 1993.  |l eng 
536 |a Detalles de la financiación: SAREC 
536 |a Detalles de la financiación: tially supportedb y the Swedish Agency for Research Cooperation with Developing Countries (SAREC), United Nations Industrial DevelopmentO rganization (UNIDO), Fundaci6n Antorchaasn d the Universityo f BuenosA ires. H.G.N. and I.G.F. are fellowsa nd I.D.A. is a career investigatoro f the Consejo Nacionadl e InvestigacioneCsi entificasy T6cnicas( Argentina). 
593 |a Instituto de Investigaciones Bioquímicas 'Fundación Campomar', Facultad de Ciencias Exactas y Naturales, University of Buenos Aires, A. Machado 151, 1405 Buenos Aires, Argentina 
690 1 0 |a (E. COLI) 
690 1 0 |a POLYAMINE 
690 1 0 |a STREPTOMYCIN 
690 1 0 |a TRANSLATION FIDELITY 
690 1 0 |a COAT PROTEIN 
690 1 0 |a POLYAMINE 
690 1 0 |a STREPTOMYCIN 
690 1 0 |a ARTICLE 
690 1 0 |a BACTERIOPHAGE 
690 1 0 |a CONTROLLED STUDY 
690 1 0 |a ESCHERICHIA COLI 
690 1 0 |a NONHUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a RNA TRANSLATION 
690 1 0 |a VIRUS INFECTION 
690 1 0 |a AUTORADIOGRAPHY 
690 1 0 |a BACTERIAL PROTEINS 
690 1 0 |a CAPSID 
690 1 0 |a ELECTROPHORESIS, GEL, TWO-DIMENSIONAL 
690 1 0 |a ELECTROPHORESIS, POLYACRYLAMIDE GEL 
690 1 0 |a ESCHERICHIA COLI 
690 1 0 |a LEVIVIRUS 
690 1 0 |a METHIONINE 
690 1 0 |a MOLECULAR WEIGHT 
690 1 0 |a POLYAMINES 
690 1 0 |a STREPTOMYCIN 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
690 1 0 |a TRANSLATION, GENETIC 
690 1 0 |a ESCHERICHIA COLI 
700 1 |a Fastame, I.G. 
700 1 |a Algranati, I.D. 
773 0 |d 1993  |g v. 1216  |h pp. 455-459  |k n. 3  |p Biochim. Biophys. Acta Gene Struct. Expr.  |x 01674781  |w (AR-BaUEN)CENRE-2259  |t BBA - Gene Structure and Expression 
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856 4 0 |u https://doi.org/10.1016/0167-4781(93)90014-5  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_01674781_v1216_n3_p455_Nastri  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01674781_v1216_n3_p455_Nastri  |y Registro en la Biblioteca Digital 
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