Microwave-assisted synthesis of pyrrolo[2,1-b]thiazoles linked to a carbohydrate moiety
Herein, we describe the synthesis of pyrrolo[2,1-b]thiazoles substituted on C-2 or C-5 with a protected carbohydrate moiety. The new fused bicyclic heterocycles were obtained via thiazole intermediates, and the N-alkylation step was assisted by microwave irradiation. The new products were completely...
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2014
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 04842caa a22005897a 4500 | ||
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| 001 | PAPER-14402 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204455.0 | ||
| 008 | 190411s2014 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84894903926 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a JHTCA | ||
| 100 | 1 | |a Barradas, J.S. | |
| 245 | 1 | 0 | |a Microwave-assisted synthesis of pyrrolo[2,1-b]thiazoles linked to a carbohydrate moiety |
| 260 | |c 2014 | ||
| 270 | 1 | 0 | |m D'Accorso, N.B.; CIHIDECAR-CONICET, Departamento de Química Orgánica, Universidad de Buenos Aires, Pabellõn 2, 1428 Buenos Aires, Argentina; email: norma@qo.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Jaguelin, S., Robert, A., Gayral, P., (1991) Eur J Med Chem, 26, p. 51 | ||
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| 504 | |a Jain, K.S., Bariwal, J.B., Kathiravan, M.K., Phoujdar, M.S., Sahne, R.S., Chauhan, B.S., Shah, A.K., Yadav, M.R., (2008) Bioorg Med Chem, 16, p. 4759 | ||
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| 504 | |a Park, J.-H., El-Gamal, M.I., Lee, Y.S., Oh, C.-H., (2011) Eur J Med Chem, 46, p. 5769 | ||
| 504 | |a Barradas, J.S., Errea, M.I., D'Accorso, N.B., Sepúlveda, C.S., Talarico, L.B., Damonte, E.B., (2008) Carbohydr Res, 343, p. 2468 | ||
| 504 | |a Barradas, J.S., Errea, M.I., D'Accorso, N.B., (2012) Carbohydr Res, 355, p. 79 | ||
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| 520 | 3 | |a Herein, we describe the synthesis of pyrrolo[2,1-b]thiazoles substituted on C-2 or C-5 with a protected carbohydrate moiety. The new fused bicyclic heterocycles were obtained via thiazole intermediates, and the N-alkylation step was assisted by microwave irradiation. The new products were completely characterized by physical and spectroscopic techniques. The cytotoxicity and antiviral activity against Junín virus of the methylated derivates was also evaluated. © 2013 HeteroCorporation. |l eng | |
| 593 | |a CIHIDECAR-CONICET, Departamento de Química Orgánica, Universidad de Buenos Aires, Pabellõn 2, 1428 Buenos Aires, Argentina | ||
| 593 | |a Departamento de Ingeniería Química, Instituto Tecnolõgico de Buenos Aires, Av. Eduardo Madero 399, 1106 Buenos Aires, Argentina | ||
| 593 | |a Departamento de Química Biolõgica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellõn 2, 1428 Buenos Aires, Argentina | ||
| 700 | 1 | |a Errea, M.I. | |
| 700 | 1 | |a Sepúlveda, C. | |
| 700 | 1 | |a Damonte, E.B. | |
| 700 | 1 | |a D'Accorso, N.B. | |
| 773 | 0 | |d 2014 |g v. 51 |h pp. 96-100 |k n. 1 |p J. Heterocycl. Chem. |x 0022152X |w (AR-BaUEN)CENRE-780 |t Journal of Heterocyclic Chemistry | |
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| 856 | 4 | 0 | |u https://doi.org/10.1002/jhet.1957 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_0022152X_v51_n1_p96_Barradas |y Handle |
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