Synthesis of D-galactofuranose-containing molecules: design of galactofuranosyl acceptors.
D-Galactofuranose (D-Galf) is present in glycoconjugates of several pathogenic microorganisms but is absent in mammals, so it is a good target for the development of chemotherapeutic agents for the treatment of microbial infections. This fact has increased interest in the synthesis of D-Galf-contain...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2014
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 03326caa a22005897a 4500 | ||
|---|---|---|---|
| 001 | PAPER-14348 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230607131901.0 | ||
| 008 | 170725s2014 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84906892311 | |
| 024 | 7 | |2 cas |a galactose, 26566-61-0, 50855-33-9, 59-23-4 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 100 | 1 | |a Marino, C. | |
| 245 | 1 | 0 | |a Synthesis of D-galactofuranose-containing molecules: design of galactofuranosyl acceptors. |
| 260 | |c 2014 | ||
| 270 | 1 | 0 | |m Marino, C.email: cmarino@qo.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 520 | 3 | |a D-Galactofuranose (D-Galf) is present in glycoconjugates of several pathogenic microorganisms but is absent in mammals, so it is a good target for the development of chemotherapeutic agents for the treatment of microbial infections. This fact has increased interest in the synthesis of D-Galf-containing molecules for corresponding glycobiological studies. The synthesis of oligosaccharides, glycoconjugates, and mimetics of D-Galf requires specific methods for the preparation of galactose derivatives in the furanosic configuration, the synthesis of appropriate acceptors, and efficient glycosylation methods for the construction of α- and β-D-Galf linkages. This review summarizes the different strategies developed for the preparation of partially protected derivatives of D-Galf, suitable as acceptors for the construction of (1→2), (1→3), (1→5), and (1→6) link- ages, and describes recent applications. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |l eng | |
| 593 | |a CIHIDECAR-CONICET-UBA, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón II, Ciudad Universitaria, 1428 Buenos Aires (Argentina). | ||
| 690 | 1 | 0 | |a CARBOHYDRATE |
| 690 | 1 | 0 | |a GALACTOSE |
| 690 | 1 | 0 | |a GLYCOCONJUGATE |
| 690 | 1 | 0 | |a POLYSACCHARIDE |
| 690 | 1 | 0 | |a CHEMISTRY |
| 690 | 1 | 0 | |a DRUG DESIGN |
| 690 | 1 | 0 | |a GALACTOFURANOSIDES |
| 690 | 1 | 0 | |a GALACTOFURANOSYL ACCEPTORS |
| 690 | 1 | 0 | |a GLYCOSYLATION |
| 690 | 1 | 0 | |a METHODOLOGY |
| 690 | 1 | 0 | |a ORGANIC SYNTHESIS |
| 690 | 1 | 0 | |a REVIEW |
| 690 | 1 | 0 | |a SYNTHESIS |
| 690 | 1 | 0 | |a CARBOHYDRATES |
| 690 | 1 | 0 | |a GALACTOFURANOSIDES |
| 690 | 1 | 0 | |a GALACTOFURANOSYL ACCEPTORS |
| 690 | 1 | 0 | |a GLYCOSYLATION |
| 690 | 1 | 0 | |a ORGANIC SYNTHESIS |
| 690 | 1 | 0 | |a CHEMISTRY TECHNIQUES, SYNTHETIC |
| 690 | 1 | 0 | |a DRUG DESIGN |
| 690 | 1 | 0 | |a GALACTOSE |
| 690 | 1 | 0 | |a GLYCOCONJUGATES |
| 690 | 1 | 0 | |a GLYCOSYLATION |
| 690 | 1 | 0 | |a POLYSACCHARIDES |
| 700 | 1 | |a Baldoni, L. | |
| 773 | 0 | |d 2014 |g v. 15 |h pp. 188-204 |k n. 2 |x 14397633 |t Chembiochem | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84906892311&doi=10.1002%2fcbic.201300638&partnerID=40&md5=62e04a2bc5d233c196fc8652c32f52e9 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1002/cbic.201300638 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_14397633_v15_n2_p188_Marino |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_14397633_v15_n2_p188_Marino |y Registro en la Biblioteca Digital |
| 961 | |a paper_14397633_v15_n2_p188_Marino |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 75301 | ||