Subcellular energy balance of Odontesthes bonariensis exposed to a glyphosate-based herbicide
Water pollution by agrochemicals is currently one of the most critical problems for the conservation of aquatic ecosystems. Glyphosate [N-(phosphonomethyl) glycine); PMG] is the main broad-spectrum post emergence herbicide used for the control of a wide range of pests in soybean crops. Adenylate ene...
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Academic Press
2015
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| LEADER | 21665caa a22020537a 4500 | ||
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| 001 | PAPER-13487 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204351.0 | ||
| 008 | 190411s2015 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84922612537 | |
| 024 | 7 | |2 cas |a adenosine diphosphate, 20398-34-9, 58-64-0; adenosine phosphate, 61-19-8, 8063-98-7; adenosine triphosphate, 15237-44-2, 56-65-5, 987-65-5; creatine phosphate, 67-07-2; glyphosate, 1071-83-6; glycine, 56-40-6, 6000-43-7, 6000-44-8; Adenine Nucleotides; Biological Markers; Glycine; glyphosate; Herbicides; Phosphocreatine; Water Pollutants, Chemical | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a EESAD | ||
| 100 | 1 | |a Menéndez-Helman, R.J. | |
| 245 | 1 | 0 | |a Subcellular energy balance of Odontesthes bonariensis exposed to a glyphosate-based herbicide |
| 260 | |b Academic Press |c 2015 | ||
| 270 | 1 | 0 | |m dos Santos Afonso, M.; INQUIMAE, Facultad de Ciencias Exactas y Naturales, CONICET-Universidad de Buenos Aires, Pabellón 2, Ciudad UniversitariaArgentina |
| 506 | |2 openaire |e Política editorial | ||
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| 504 | |a (1994) Glyphosate, , Environmental Health Criteria 159. Geneva | ||
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| 520 | 3 | |a Water pollution by agrochemicals is currently one of the most critical problems for the conservation of aquatic ecosystems. Glyphosate [N-(phosphonomethyl) glycine); PMG] is the main broad-spectrum post emergence herbicide used for the control of a wide range of pests in soybean crops. Adenylate energy charge (AEC) reflects the energy balance of the cells, a measure of the energy available from the adenylate pool: adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP). Background adenylates, phosphagens and the AEC index of two year old Odontesthes bonariensis were determined in some tissues by HPLC, and the impact on subcellular energy balance of sublethal glyphosate-based herbicide exposure was analyzed. The doses used were 0 (control tank), 1 or 10mg PMGL-1, trials were carried out during 15 days. AEC values in brain, liver and muscle from control fish were 0.37±0.02, 0.49±0.05 and 0.56±0.03, respectively (means±SEM). While brain ATP concentrations were undetectable (hence low values of AEC), the muscle tissue showed the highest concentrations of the more energetic molecules: 0.18μmole ATPg-1 and 8μmole phosphocreatineg-1 (PCrg-1). In the brain, no significant changes were detected in exposed fish compared to controls. Instead, in both the liver and muscle of animals exposed to the highest concentration of the herbicide, significant changes in the AEC (reduction of 26% and 15%, p<0.05) with respect to the control group were determined. Chronic exposure (15 days) of Odontesthes bonariensis to 1 and 10mgL-1 of formulated glyphosate did not affect brain AEC. However, the highest concentration of the herbicide produced a significant decrease in liver and muscle AEC manifesting adverse sublethal effects on the energy metabolism. These results suggest the usefulness of AEC as a biomarker of fish glyphosate exposure. © 2015 Elsevier Inc. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, PIP 1673/12 grant | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Ministerio de la Producción, Ciencia y Tecnología | ||
| 536 | |a Detalles de la financiación: Fondo para la Investigación Científica y Tecnológica, PICT2012-1537, PICT2007-00371 | ||
| 536 | |a Detalles de la financiación: Secretaría de Ciencia y Técnica, Universidad de Buenos Aires, 20020100100750 | ||
| 536 | |a Detalles de la financiación: The authors acknowledge the Universidad de Buenos Aires (UBA) and the IIB-INTECH (CONICET – UNSAM), where this project was carried out. Authors also gratefully acknowledge the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina (CONICET, PIP 1673/12 grant), Ministerio de Ciencia y Tecnología , Agencia Nacional de Promoción Científica y Tecnológica , Fondo para la Investigación Científica y Tecnológica (MINCyT-ANPCyT-FONCyT, PICT2007-00371 and PICT2012-1537 grants) and Universidad de Buenos Aires (UBACyT 20020100100750 grant) for financial support. | ||
| 593 | |a INQUIMAE, Facultad de Ciencias Exactas y Naturales, CONICET-Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, Ciudad Autónoma de Buenos Aires, C1428EHA, Argentina | ||
| 593 | |a Laboratorio de Ictiofisiología y Acuicultura, Instituto de Investigaciones Biotecnológicas, Instituto Tecnologico de Chascomus (IIB-INTECH) CONICET - UNSAM. B7130IWA Chascomus, Buenos Aires, Argentina | ||
| 593 | |a Programa de Ecofisiología Aplicada (PRODEA), Instituto de Ecología y Desarrollo Sustentable (INEDES), Universidad Nacional de Luján, Luján, B6700ZBA, Argentina | ||
| 690 | 1 | 0 | |a ADENYLATE ENERGY CHARGE (AEC) |
| 690 | 1 | 0 | |a BASED HERBICIDE |
| 690 | 1 | 0 | |a BIOMARKERS |
| 690 | 1 | 0 | |a GLYPHOSATE |
| 690 | 1 | 0 | |a ODONTESTHES BONARIENSIS |
| 690 | 1 | 0 | |a PHOSPHAGENS |
| 690 | 1 | 0 | |a ADENOSINE DIPHOSPHATE |
| 690 | 1 | 0 | |a ADENOSINE PHOSPHATE |
| 690 | 1 | 0 | |a ADENOSINE TRIPHOSPHATE |
| 690 | 1 | 0 | |a CREATINE PHOSPHATE |
| 690 | 1 | 0 | |a GLYPHOSATE |
| 690 | 1 | 0 | |a ADENINE NUCLEOTIDE |
| 690 | 1 | 0 | |a BIOLOGICAL MARKER |
| 690 | 1 | 0 | |a GLYCINE |
| 690 | 1 | 0 | |a GLYPHOSATE |
| 690 | 1 | 0 | |a HERBICIDE |
| 690 | 1 | 0 | |a WATER POLLUTANT |
| 690 | 1 | 0 | |a AGROCHEMICAL |
| 690 | 1 | 0 | |a BIOMARKER |
| 690 | 1 | 0 | |a FISH |
| 690 | 1 | 0 | |a GLYPHOSATE |
| 690 | 1 | 0 | |a POLLUTION EXPOSURE |
| 690 | 1 | 0 | |a SUBLETHAL EFFECT |
| 690 | 1 | 0 | |a ADSORPTION KINETICS |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL TISSUE |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a BRAIN LEVEL |
| 690 | 1 | 0 | |a CELL ENERGY |
| 690 | 1 | 0 | |a CONCENTRATION (PARAMETERS) |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a DEGRADATION KINETICS |
| 690 | 1 | 0 | |a ENERGY BALANCE |
| 690 | 1 | 0 | |a ENVIRONMENTAL EXPOSURE |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a FISH |
| 690 | 1 | 0 | |a HIGH PERFORMANCE LIQUID CHROMATOGRAPHY |
| 690 | 1 | 0 | |a LIVER LEVEL |
| 690 | 1 | 0 | |a LONG TERM EXPOSURE |
| 690 | 1 | 0 | |a MALE |
| 690 | 1 | 0 | |a MUSCLE LEVEL |
| 690 | 1 | 0 | |a MUSCLE TISSUE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a ODONTESTHES BONARIENSIS |
| 690 | 1 | 0 | |a WATER POLLUTION |
| 690 | 1 | 0 | |a ANALOGS AND DERIVATIVES |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a BRAIN |
| 690 | 1 | 0 | |a DOSE RESPONSE |
| 690 | 1 | 0 | |a DRUG EFFECTS |
| 690 | 1 | 0 | |a ENERGY METABOLISM |
| 690 | 1 | 0 | |a LIVER |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a MUSCLE |
| 690 | 1 | 0 | |a SMEGMAMORPHA |
| 690 | 1 | 0 | |a TOXICITY |
| 690 | 1 | 0 | |a WATER POLLUTANT |
| 690 | 1 | 0 | |a ANIMALIA |
| 690 | 1 | 0 | |a GLYCINE MAX |
| 690 | 1 | 0 | |a ODONTESTHES BONARIENSIS |
| 690 | 1 | 0 | |a ADENINE NUCLEOTIDES |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a BIOLOGICAL MARKERS |
| 690 | 1 | 0 | |a BRAIN |
| 690 | 1 | 0 | |a DOSE-RESPONSE RELATIONSHIP, DRUG |
| 690 | 1 | 0 | |a ENERGY METABOLISM |
| 690 | 1 | 0 | |a GLYCINE |
| 690 | 1 | 0 | |a HERBICIDES |
| 690 | 1 | 0 | |a LIVER |
| 690 | 1 | 0 | |a MUSCLES |
| 690 | 1 | 0 | |a PHOSPHOCREATINE |
| 690 | 1 | 0 | |a SMEGMAMORPHA |
| 690 | 1 | 0 | |a WATER POLLUTANTS, CHEMICAL |
| 700 | 1 | |a Miranda, L.A. | |
| 700 | 1 | |a dos Santos Afonso, M. | |
| 700 | 1 | |a Salibián, A. | |
| 773 | 0 | |d Academic Press, 2015 |g v. 114 |h pp. 157-163 |p Ecotoxicol. Environ. Saf. |x 01476513 |w (AR-BaUEN)CENRE-4483 |t Ecotoxicology and Environmental Safety | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/j.ecoenv.2015.01.014 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01476513_v114_n_p157_MenendezHelman |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01476513_v114_n_p157_MenendezHelman |y Registro en la Biblioteca Digital |
| 961 | |a paper_01476513_v114_n_p157_MenendezHelman |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 74440 | ||