Studies on potato tuber phosphorylase-catalyzed reaction in the absence of an exogenous acceptor. I. Characterization and properties of the enzyme

Phosphorylase II from potato tuber has been subjected to several purification procedures in order to: (a) separate the unprimed activity from the primed one coexisting in the enzymatic preparation, and (b) eliminate endogenous glucan and/or glycoproteins. Large-scale analytical nondenaturing gel ele...

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Autor principal: Sivak, M.N
Otros Autores: Tandecarz, J.S, Cardini, C.E
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1981
Acceso en línea:Registro en Scopus
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024 7 |2 scopus  |a 2-s2.0-0019741739 
024 7 |2 cas  |a phosphorylase, 9035-74-9; Isoenzymes; Phosphorylases, EC 2.4.1.- 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a ABBIA 
100 1 |a Sivak, M.N. 
245 1 0 |a Studies on potato tuber phosphorylase-catalyzed reaction in the absence of an exogenous acceptor. I. Characterization and properties of the enzyme 
260 |c 1981 
270 1 0 |m Sivak, M.N.; Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490, 1428 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Tandecarz, Sivak, Cardini, (1978) Biochem. Biophys. Res. Commun, 82, pp. 157-164 
504 |a Feigin, Frederick, Wolf, (1951) Fed. Proc, 10, pp. 181-182. , 3rd ed 
504 |a Slabnik, Frydman, (1970) Biochem. Biophys. Res. Commun, 38, pp. 709-714 
504 |a Frederick, De novo Synthesis of Polyglucans by a Phosphorylase Isoenzyme in Algae (1971) Physiologia Plantarum, 25, pp. 32-34 
504 |a Kamogawa, Fukui, Nikuni, (1968) J. Biochem, 63, pp. 361-369 
504 |a Burr, Nelson, (1975) Eur. J. Biochem, 56, pp. 539-546 
504 |a Thomas, Kaith, Schlender, Larner, (1968) Anal. Biochem, 25, pp. 486-499 
504 |a Tandecarz, Lavintman, Cardini, (1975) Biochim. Biophys. Acta, 399, pp. 345-355 
504 |a Davis, (1964) Ann. N. Y. Acad. Sci, 121, pp. 404-427 
504 |a Tandecarz, Lavitman, Cardini, (1→4)-α-d-glucan phosphorylase [(1→4)-α-d-glucan:orthophosphate glucosyltransferase] isoenzymes from sweet corn seed embryo (1973) Carbohydrate Research, 19, pp. 385-392 
504 |a Hedrick, Smith, (1968) Arch. Biochem. Biophys, 126, pp. 155-164 
504 |a Ziegler, Harrison, Leberman, (1974) Virology, 59, pp. 509-515 
504 |a Fairbanks, Steck, Wallanch, (1971) Biochemistry, 10, pp. 2606-2616 
504 |a Bonner, Laskey, (1974) Eur. J. Biochem, 46, pp. 83-88 
504 |a Laskey, Mills, (1975) Eur. J. Biochem, 56, pp. 335-341 
504 |a Martin, Ames, (1961) J. Biol. Chem, 236, pp. 1372-1379 
504 |a Lowry, Rosebrough, Farr, Randall, (1951) J. Biol. Chem, 193, pp. 265-275 
504 |a Hollo, Laszlo, Hoschke, Biosynthese der Stärke V.. Untersuchung der optimalen Reaktionsbedingungen der Amylose-Synthese (1965) Starch - Stärke, 17, pp. 377-381 
504 |a Hollo, Laszlo, Juhasz, Die Biosynthese der Stärke IX.. Die optimalen Bedingungen der Phosphorolyse (1967) Starch - Stärke, 19, pp. 246-250 
504 |a Hollo, Laszlo, Hoschke, Die Biosynthese der Stärke. 3. Mitteilung: Die Herstellung von Kartoffelphosphorylase großer Reinheit mittels DEAE -Cellulose- Säulenchromatographie (1964) Starch - Stärke, 16, pp. 243-246 
504 |a Kawaguchi, Fox, Holmes, Boyer, Preiss, (1978) Arch. Biochem. Biophys, 190, pp. 385-397 
504 |a Fox, Kawaguchi, Greenberg, Preiss, (1976) Biochemistry, 15, pp. 849-857 
504 |a Lloyd, (1976) Concanavalin A as a Tool, pp. 329-331. , H. Bittiger, H.P. Schnebli, Wiley, London 
504 |a Lee, (1960) Biochim. Biophys. Acta, 43, pp. 18-24 
504 |a Iwata, Fukui, (1973) FEBS Lett, 36, pp. 222-226 
504 |a Illingworth, Brown, Cori, (1961) Proc. Nat. Acad. Sci. USA, 47, pp. 469-478. , 3rd ed 
504 |a Tsai, Nelson, (1969) Plant Physiol, 44, pp. 159-167 
504 |a Frydman, Slabnik, (1973) Ann. N. Y. Acad. Sci, 210, pp. 153-169 
504 |a Fredrick, (1975) Plant Sci. Lett, 5, pp. 131-135 
520 3 |a Phosphorylase II from potato tuber has been subjected to several purification procedures in order to: (a) separate the unprimed activity from the primed one coexisting in the enzymatic preparation, and (b) eliminate endogenous glucan and/or glycoproteins. Large-scale analytical nondenaturing gel electrophoresis and affinity chromatography on concanavalin A-Sepharose 4B succeeded in removing endogenous glycoproteins without any effect on the unprimed activity. In addition, phosphorolysis or glucoamylase treatment of the enzymatic preparation did not abolish the phosphorylase-catalyzed reaction in the absence of an exogenous acceptor. However, no separation between both activities, primed and unprimed, could be achieved either by the above-mentioned methods or by sucrose density gradient centrifugation. Based on sodium dodecyl sulfate-urea-gel electrophoresis, a molecular weight of about 96,000 was found for the phosphorylase II subunit. Molecular weight determination by nondenaturing gel electrophoresis at 5, 6, 7, and 8% acrylamide and by ultracentrifugation on sucrose density gradients suggested that the native enzyme is a dimer, as are other phosphorylases. © 1981.  |l eng 
593 |a Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales, Obligado 2490, 1428 Buenos Aires, Argentina 
690 1 0 |a ISOENZYME 
690 1 0 |a PHOSPHORYLASE 
690 1 0 |a ARTICLE 
690 1 0 |a ENZYME SPECIFICITY 
690 1 0 |a ENZYMOLOGY 
690 1 0 |a HEAT 
690 1 0 |a ISOLATION AND PURIFICATION 
690 1 0 |a KINETICS 
690 1 0 |a METABOLISM 
690 1 0 |a MOLECULAR WEIGHT 
690 1 0 |a PLANT 
690 1 0 |a HEAT 
690 1 0 |a ISOENZYMES 
690 1 0 |a KINETICS 
690 1 0 |a MOLECULAR WEIGHT 
690 1 0 |a PHOSPHORYLASES 
690 1 0 |a PLANTS 
690 1 0 |a SUBSTRATE SPECIFICITY 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
700 1 |a Tandecarz, J.S. 
700 1 |a Cardini, C.E. 
773 0 |d 1981  |g v. 212  |h pp. 525-536  |k n. 2  |p Arch. Biochem. Biophys.  |x 00039861  |w (AR-BaUEN)CENRE-1377  |t Archives of Biochemistry and Biophysics 
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856 4 0 |u https://hdl.handle.net/20.500.12110/paper_00039861_v212_n2_p525_Sivak  |y Handle 
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