Modelling and operation of a turbidity-meter for on-line monitoring of microbial growth in fermenters

The PROIMI-2 prototype turbidity-meter for measuring cell concentrations in stirred tanks, has been designed and constructed using theories based on kinetic laws and the general principles of cell growth. Laboratory assays were carried out with batch cultures of Bacillus amyloliquefaciens, Zymomonas...

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Autor principal: Castro, G.R
Otros Autores: Andribet, E.P, Ducrey, L.M, Garro, O.A, Siñeriz, F.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1995
Acceso en línea:Registro en Scopus
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100 1 |a Castro, G.R. 
245 1 0 |a Modelling and operation of a turbidity-meter for on-line monitoring of microbial growth in fermenters 
260 |c 1995 
270 1 0 |m Castro, G.R.; Cátedra de Microbiología Superior, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Avda. Belgrano y Pje, Caseros, 4000 Tucumán, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Pirt, (1975) Principle of Microbe and Cell Cultivation, pp. 15-21. , S.J. Pirt, Blackwell Scientific Publications, London 
504 |a Koch, Growth measurement (1981) Manual Methods for General Bacteriology, pp. 179-217. , P. Gerhardt, R.G.E. Murray, R.N. Costilow, E.W. Nester, W.A. Wood, N.R. Krieg, G. Briggs Phillips, American Society for Microbiology, Washington DC 
504 |a Hancher, Thacker, Phares, A fiber-optic retroflective turbidity-meter for continuously monitoring cell concentration during fermentation (1974) Biotechnol. Bioeng., 15, pp. 475-484 
504 |a Lima Filho, Ledingham, Continuous measurement of biomass concentration in laboratory scale fermenters using a led-electrode system (1987) Biotechnol. Tech., 1, pp. 145-150 
504 |a Nielsen, Nikolajsen, Villadsen, FIA for on-line monitoring of important lactic acid fermentation variables (1989) Biotechol. Bioeng., 33, pp. 1127-1134 
504 |a Ohashi, Watabe, Watanabe, Sensors and instrumentation: steam-sterilizable dissolved oxygen sensor and cell mass sensor for on-line fermentation system control (1979) Biotechnol. Bioeng. Symp., 9, pp. 103-116 
504 |a Ortmanis, Patterson, Neufeld, Evaluation of a new turbidimeter design incorporating a microprocessor-controlled variable pathlength cuvette (1991) Enzyme Microb. Technol., 13, pp. 450-455 
504 |a Thatipamala, Rohani, Hill, Spectrophotometric method for high biomass concentration measurements (1991) Biotechnol. Bioeng., 38, pp. 1007-1011 
504 |a Konstantin, Pambayun, Matanguihan, Yoshida, Peruish, Hu, On-line monitoring of hybridoma cell growth using a laser turbidity sensor (1992) Biotechnol. Bioeng., 40, pp. 1337-1342 
504 |a Yano, Madsuki, Nishizawa, Photometric measurement of high cell density by continuous dilution of broth with circulating system (1992) J. Ferment. Bioeng., 74, pp. 100-103 
504 |a Castro, Méndez, Siñeriz, Amylolytic enzymes produced by Bacillus amyloliquefaciens MIR-41 in batch and continuous culture (1993) J. Chem. Tech. Biotechnol., 53, pp. 289-294 
504 |a Rodríguez, Callieri, High yield conversion of sucrose into ethanol by a flocculent Zymomonas sp isolated from sugarcane juice (1986) Biotechnology Letters, 8, pp. 745-748 
504 |a Glasstone, The Maxwell-Boltzman distribution law (1946) Textbook of Physical Chemisry, New York, pp. 270-275. , D. Van Nostrand Co. Inc 
504 |a Granville, (1952) Elements of the Differential and Integral Calculus, pp. 641-649. , Ginn & Co, Boston 
504 |a Zhong, Fujiyama, Seki, Yoshida, On-line monitoring of cell concentration of Perilla frutescens in a bioreactor (1993) Biotechnol. Bioeng., 42, pp. 542-546 
504 |a Yamane, Fed batch culture automated by use of continuously measured cell concentrations and cell volume (1992) Biotechnol. Bioeng., 39, pp. 550-555 
520 3 |a The PROIMI-2 prototype turbidity-meter for measuring cell concentrations in stirred tanks, has been designed and constructed using theories based on kinetic laws and the general principles of cell growth. Laboratory assays were carried out with batch cultures of Bacillus amyloliquefaciens, Zymomonas mobilis and Saccharomyces cerevisae. The signals showed a good correlation with optical density and biomass. In the latter case up to 4·0 g per dm3 expressed as dry weight could be monitored successfully. © 1995.  |l eng 
536 |a Detalles de la financiación: Third World Academy of Sciences 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas 
536 |a Detalles de la financiación: The authors gratefully acknowledge the financial support for this work from CONICET (Argentina), Third World Academy of Sciences (Italy) and Sarec (Sweden). We express our appreciation to Drs D. M. and J. T. F. Spencer for language advice. We thank Mrs H. A. L. AbregG and Mr S. Borchia for material preparation. 
593 |a Cátedra de Microbiología Superior, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Avda. Belgrano y Pje, Caseros, 4000 Tucumán, Argentina 
593 |a Laboratorio de Microbiología, Departamento Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428 Bueos Aires, Argentina 
700 1 |a Andribet, E.P. 
700 1 |a Ducrey, L.M. 
700 1 |a Garro, O.A. 
700 1 |a Siñeriz, F. 
773 0 |d 1995  |g v. 30  |h pp. 767-772  |k n. 8  |p Process Biochem.  |x 13595113  |t Process Biochemistry 
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