Experimental infection of suckling mice with a host range mutant of junin virus
Experimental infection of three mouse strains with a non‐pathogenic mutant of Junin virus named C167 was compared with respect to the parental XJC13 strain. After intracerebral (ic) or intraperitoneal inoculation, XJC13 was highly virulent for 2 day‐old C3H/HeJ, OF1, and BALB/cJ mouse strains, where...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1991
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 05974caa a22008537a 4500 | ||
|---|---|---|---|
| 001 | PAPER-11896 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204206.0 | ||
| 008 | 190411s1991 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0025878751 | |
| 024 | 7 | |2 cas |a Antibodies, Viral | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 100 | 1 | |a Scolaro, L.A. | |
| 245 | 1 | 0 | |a Experimental infection of suckling mice with a host range mutant of junin virus |
| 260 | |c 1991 | ||
| 270 | 1 | 0 | |m Scolaro, L.A.; Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas Y Naturales, Ciudad Universitaria, Pabellón 2, Buenos Aires, 1428, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Boxaca, MC, Giovanniello, OA, Nota, NR, Nejamkis, MR, de Guerrero, LB, Frigerio, MJ, Estudio de la infección experimental del ratón por virus Junín: Cuadro clínico y susceptibilidad (1973) Revista de la Asociación Argentina de Microbiología, 5, pp. 2-12 | ||
| 504 | |a Campetella, OE, Galassi, NV, Sanjuan, N, Barrios, HA, Susceptible adult murine model for Junin virus (1988) Journal of Medical Virology, 26, pp. 443-448 | ||
| 504 | |a Candurra, NA, Damonte, EB, Coto, CE, Antigenic relationships between attenuated and pathogenic strains of Junin virus (1989) Journal of Medical Virology, 27, pp. 145-150 | ||
| 504 | |a Coto, CE, Damonte, EB, Calello, MA, Weissenbacher, MC, Protection of guinea pigs inoculated with Tacaribe virus against lethal doses of Junin virus (1980) Journal of Infectious Diseases, 141, pp. 389-393 | ||
| 504 | |a Damonte, EB, Coto, CE, Calello, MA, Weissenbacher, MC, Inmunización heteróloga contra virus Junín. Protección temprana. Medicina (B (1978) Aires), 38, pp. 226-232 | ||
| 504 | |a Nota, NR, Nejamkis, MR, Giovanniello, OA, Patogenia de la encefalitis del ratón infectado con virus Junín. Medicina (B (1977) Aires), 37, pp. 114-120 | ||
| 504 | |a Oldstone, MBA, Ahmed, R, Buchmeier, MJ, Blount, P, Tishon, A, Perturbation of differentiated functions during viral infection in vivo. I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency (1985) Virology, 142, pp. 158-174 | ||
| 504 | |a Scolaro, LA, Mersich, SE, Damonte, EB, Reduced virulence of a Junin virus mutant is associated with restricted multiplication in murine cells (1989) Virus Research, 13, pp. 283-294 | ||
| 504 | |a Scolaro, LA, Mersich, SE, Damonte, EB, A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein (1990) Archives of Virology, 111, pp. 257-262 | ||
| 504 | |a Weissenbacher, MC, Laguens, RP, Coto, CE, Argentine Hemorrhagic Fever (1987) Current Topics in Microbiology and Immunology, 134, pp. 79-116 | ||
| 504 | |a Yamada, M, Arao, Y, Uno, F, Nii, S, Mechanism of differences in pathogenicity between two variants of a laboratory strain of Herpes simplex virus type 1 (1986) Microbiology and Immunology, 30, pp. 1259-1270 | ||
| 520 | 3 | |a Experimental infection of three mouse strains with a non‐pathogenic mutant of Junin virus named C167 was compared with respect to the parental XJC13 strain. After intracerebral (ic) or intraperitoneal inoculation, XJC13 was highly virulent for 2 day‐old C3H/HeJ, OF1, and BALB/cJ mouse strains, whereas its derivative C167 was attenuated. Survival of the C167‐infected mouse was associated with a restricted replication at the site of inoculation which would impair spread of virus. Thus, the reduced virulence of C167 for suckling mice is independent of the mouse strain and the route of viral entry. When C167 was preinoculated ic I0 days before the challenge inoculation with XJC13 by the same route, mice were partially protected from lethal infection. Since neutralizing antibodies were first detected at 30 days post‐infection, an interference mechanism is postulated as a mechanism of protection of the mice. Copyright © 1991 Wiley‐Liss, Inc., A Wiley Company |l eng | |
| 593 | |a Laboratorio de Virología, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a ATTENUATED MUTANT |
| 690 | 1 | 0 | |a MOUSE STRAIN SUSCEPTIBILITY |
| 690 | 1 | 0 | |a PROTECTION |
| 690 | 1 | 0 | |a NEUTRALIZING ANTIBODY |
| 690 | 1 | 0 | |a VIRUS VACCINE |
| 690 | 1 | 0 | |a ANIMAL EXPERIMENT |
| 690 | 1 | 0 | |a ANIMAL MODEL |
| 690 | 1 | 0 | |a ANTIBODY DETECTION |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a IMMUNE RESPONSE |
| 690 | 1 | 0 | |a IMMUNIZATION |
| 690 | 1 | 0 | |a JUNIN VIRUS |
| 690 | 1 | 0 | |a MOUSE |
| 690 | 1 | 0 | |a NEWBORN |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROVOCATION TEST |
| 690 | 1 | 0 | |a VIRUS ATTENUATION |
| 690 | 1 | 0 | |a VIRUS INFECTION |
| 690 | 1 | 0 | |a VIRUS MUTANT |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a ANTIBODIES, VIRAL |
| 690 | 1 | 0 | |a ARENAVIRUSES, NEW WORLD |
| 690 | 1 | 0 | |a DISEASE MODELS, ANIMAL |
| 690 | 1 | 0 | |a KINETICS |
| 690 | 1 | 0 | |a MICE |
| 690 | 1 | 0 | |a MICE, INBRED STRAINS |
| 690 | 1 | 0 | |a MUTATION |
| 690 | 1 | 0 | |a NEUTRALIZATION TESTS |
| 690 | 1 | 0 | |a PLAQUE ASSAY |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 690 | 1 | 0 | |a VERO CELLS |
| 690 | 1 | 0 | |a VIRULENCE |
| 651 | 4 | |a HEMORRHAGIC FEVER, AMERICAN | |
| 700 | 1 | |a Mersich, S.E. | |
| 700 | 1 | |a Damonte, E.B. | |
| 773 | 0 | |d 1991 |g v. 34 |h pp. 237-240 |k n. 4 |p J. Med. Virol. |x 01466615 |t Journal of Medical Virology | |
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| 856 | 4 | 0 | |u https://doi.org/10.1002/jmv.1890340408 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01466615_v34_n4_p237_Scolaro |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01466615_v34_n4_p237_Scolaro |y Registro en la Biblioteca Digital |
| 961 | |a paper_01466615_v34_n4_p237_Scolaro |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 72849 | ||