Requirement of cholesterol in the viral envelope for dengue virus infection
•Cholesterol in the virion envelope is essential for dengue virus infectivity.•The four dengue serotypes are similarly inactivated by cholesterol-extracting drugs.•Dengue virus uncoating is blocked in infection with cholesterol-depleted virions.•Virion treatment with exogenous cholesterol exert also...
Guardado en:
| Autor principal: | |
|---|---|
| Otros Autores: | |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2013
|
| Materias: | |
| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 16815caa a22014537a 4500 | ||
|---|---|---|---|
| 001 | PAPER-11518 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518204141.0 | ||
| 008 | 190411s2013 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-84877621671 | |
| 024 | 7 | |2 cas |a cholesterol, 57-88-5; nystatin, 1400-61-9, 34786-70-4, 62997-67-5; protein, 67254-75-5; Cholesterol, 57-88-5; Membrane Lipids; viral envelope lipids | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a VIRED | ||
| 100 | 1 | |a Carro, A.C. | |
| 245 | 1 | 0 | |a Requirement of cholesterol in the viral envelope for dengue virus infection |
| 260 | |c 2013 | ||
| 270 | 1 | 0 | |m Damonte, E.B.; Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IQUIBICEN-CONICET, Ciudad Universitaria, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina; email: edamonte@qb.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Acosta, E.G., Castilla, V., Damonte, E.B., Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis (2008) Journal of General Virology, 89, pp. 474-484 | ||
| 504 | |a Acosta, E.G., Castilla, V., Damonte, E.B., Alternative infectious entry pathways for dengue virus serotypes into mammalian cells (2009) Cellular Microbiology, 11, pp. 1533-1549 | ||
| 504 | |a Acosta, E.G., Castilla, V., Damonte, E.B., Infectious dengue-1 virus entry into mosquito C6/36 cells (2011) Virus Research, 160, pp. 173-179 | ||
| 504 | |a Acosta, E.G., Castilla, V., Damonte, E.B., Differential requirements in endocytic trafficking for penetration of dengue virus (2012) PLoS ONE, 7, pp. e44835 | ||
| 504 | |a Aizaki, H., Morikawa, K., Fukasawa, M., Hara, H., Inoue, Y., Tani, H., Saito, K., Suzuki, T., Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection (2008) Journal of Virology, 82, pp. 5715-5724 | ||
| 504 | |a Anderson, H.A., Chen, Y., Norkin, L.C., Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae (1996) Molecular Biology of the Cell, 7, pp. 1825-1834 | ||
| 504 | |a Bavari, S., Bosio, C.M., Wiegand, E., Ruthel, G., Will, A.B., Geisbert, T.W., Hevey, M., Aman, M.J., Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses (2002) Journal of Experimental Medicine, 195, pp. 593-602 | ||
| 504 | |a Bender, F.C., Whitbeck, J.C., Ponce, D.L., Lou, H., Eisenberg, R.J., Cohen, G.H., Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry (2003) Journal of Virology, 77, pp. 9542-9552 | ||
| 504 | |a Bremer, C.M., Bung, C., Kott, N., Hardt, M., Glebe, D., Hepatitis B virus infection is dependent on cholesterol in the viral envelope (2009) Cellular Microbiology, 11, pp. 249-260 | ||
| 504 | |a Brown, E.L., Lyles, D.S., A novel method for analysis of membrane microdomains: vesicular stomatitis virus glycoprotein microdomains change in size during infection, and those outside of budding sites resemble sites of virus budding (2003) Virology, 310, pp. 343-358 | ||
| 504 | |a Bulich, R., Aaskov, J.G., Nuclear localization of dengue 2 virus core protein detected with monoclonal antibodies (1992) Journal of General Virology, 73, pp. 2999-3003 | ||
| 504 | |a Clayton, R.B., The utilization of sterols by insects (1964) Journal of Lipid Research, 15, pp. 3-19 | ||
| 504 | |a Clemente, R., de Parseval, A., Perez, M., de la Torre, J.C., Borna disease virus requires cholesterol in both cellular membrane and viral envelope for efficient virus entry (2009) Journal of Virology, 83, pp. 2655-2662 | ||
| 504 | |a Desplanques, A.S., Nauwynck, N.J., Vercauteren, D., Geens, T., Favoreel, H.W., Plasma membrane cholesterol is required for efficient pseudorabies virus entry (2008) Virology, 376, pp. 339-345 | ||
| 504 | |a Desplanques, A.S., Pontes, M., De Corte, N., Verheyen, N., Nauwynck, N.J., Vercauteren, D., Favoreel, H.W., Cholesterol depletion affects infectivity and stability of pseudorabies virus (2010) Virus Research, 152, pp. 180-183 | ||
| 504 | |a Funk, A., Mhamdi, M., Hohenberg, H., Heeren, J., Reimer, R., Lambert, C., Prange, R., Sirma, H., Duck hepatitis B virus requires cholesterol for endosomal escape during virus entry (2008) Journal of Virology, 82, pp. 10532-10542 | ||
| 504 | |a Graham, D.R., Chertova, E., Hilburn, J.M., Arthur, L.O., Hildreth, J.E., Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts (2003) Journal of Virology, 77, pp. 8237-8248 | ||
| 504 | |a Guzmán, M.G., Halstead, S.B., Artsob, H., Buchy, P., Farrar, J., Gubler, D.J., Hunsperger, E., Peeling, R.W., Dengue: a continuing global threat (2010) Nature Reviews Microbiology, 8, pp. S7-S16 | ||
| 504 | |a Hafer, A., Whittlesey, R., Brown, D.T., Hernandez, R., Differential incorporation of cholesterol by Sindbis virus grown in mammalian or insect cells (2009) Journal of Virology, 83, pp. 9113-9121 | ||
| 504 | |a Hambleton, S., Steinberg, S.P., Gershon, M.D., Gershon, A.A., Cholesterol dependence of varicella-zoster virion entry into target cells (2007) Journal of Virology, 81, pp. 7548-7558 | ||
| 504 | |a Hidari, K.I., Takahashi, N., Arihara, M., Nagaoka, M., Morita, K., Suzuki, T., Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga (2008) Biochem. Biophys. Res. Commun, 376, pp. 91-95 | ||
| 504 | |a Huang, H., Li, Y., Sadaoka, T., Tang, H., Yamamoto, T., Yamanishi, K., Mori, Y., Human herpesvirus 6 envelope cholesterol is required for virus entry (2006) Journal of General Virology, 87, pp. 277-285 | ||
| 504 | |a Ilangumaran, S., Hoessli, D.C., Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane (1998) Biochemical Journal, 335, pp. 433-440 | ||
| 504 | |a Imhoff, H., von Messling, V., Herrler, G., Haas, L., Canine distemper virus infection requires cholesterol in the viral envelope (2007) Journal of Virology, 81, pp. 4158-4165 | ||
| 504 | |a Kaptein, S.J.F., De Burghgraeve, T., Froeyen, M., Pastorino, B., Alen, M.M.F., Mondotte, J.A., Herdewijn, P., Neyts, J., A derivative of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro (2010) Antimicrobial Agents and Chemotherapy, 54, pp. 5269-5280 | ||
| 504 | |a Krebs, K.C., Lan, Q., Isolation and expression of a sterol carrier protein-2 gene from the yellow fever mosquito, Aedes aegypti (2003) Insect Molecular Biology, 12, pp. 51-60 | ||
| 504 | |a Kyle, J.L., Harris, E., Global spread and persistence of dengue (2008) Annual Review of Microbiology, 62, pp. 71-92 | ||
| 504 | |a Lange, Y., Ye, J., Rigney, M., Steck, T.L., Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol (1999) Journal of Lipid Research, pp. 2264-2270 | ||
| 504 | |a Lee, C.J., Lin, H.R., Liao, C.L., Lin, Y.L., Cholesterol effectively blocks entry of flavivirus (2008) Journal of Virology, 82, pp. 6470-6480 | ||
| 504 | |a Liao, Z., Cimakasky, L.M., Hampton, R., Nguyen, D.H., Hildreth, J.E., Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1 (2001) AIDS Research and Human Retroviruses, 17, pp. 1009-1019 | ||
| 504 | |a Lu, X., Xiong, Y., Silver, J., Asymmetric requirement for cholesterol in receptor-bearing but not envelope-bearing membranes for fusion mediated by ecotropic murine leukemia virus (2002) Journal of Virology, 76, pp. 6701-6709 | ||
| 504 | |a Moore, N.F., Patzer, E.J., Shaw, J.M., Thompson, T.E., Wagner, R.R., Interaction of vesicular stomatitis vírus with lipid vesicles: depletion of cholesterol and effect on virion membranes (1978) Journal of Virology, 27, pp. 320-329 | ||
| 504 | |a Mosso, C., Galván-Mendoza, I.J., Ludert, J.E., del Angel, R.M., Endocytic pathway followed by dengue virus to infect the mosquito cell line C6/36 HT (2008) Virology, 378, pp. 193-199 | ||
| 504 | |a Peng, T., Wang, J.L., Chen, W., Zhang, J.L., Gao, N., Chen, Z.T., Xu, X.F., An, J., Entry of dengue virus serotype 2 into ECV304 cells depends on clathrin-dependent endocytosis, but not on caveolae-dependent endocytosis (2009) Canadian Journal of Microbiology, 55, pp. 139-145 | ||
| 504 | |a Ren, X., Glende, J., Yin, J., Schwegmann-Wessels, C., Herrler, G., Importance of cholesterol for infection of cells by transmissible gastroenteritis virus (2008) Virus Research, 137, pp. 220-224 | ||
| 504 | |a Reyes-del Valle, J., Chávez-Salinas, S., Medina, F., del Angel, R.M., Heat shock protein 90 and heat shock protein 70 are components of dengue virus receptor complex in human cells (2005) Journal of Virology, 79, pp. 4557-4567 | ||
| 504 | |a Scheiffele, P., Rietveld, A., Wilk, T., Simons, K., Influenza viruses select ordered lipid domains during budding from the plasma membrane (1999) Journal of Biological Chemistry, 274, pp. 2038-2044 | ||
| 504 | |a Schlie, K., Maisa, A., Lennartz, F., Stroher, U., Garten, W., Strecker, T., Characterization of Lassa virus glycoprotein oligomerization and influence of cholesterol on virus replication (2010) Journal of Virology, 84, pp. 983-992 | ||
| 504 | |a Sousa, I.P., Carvalho, C.A.M., Ferreira, D.F., Weissmuller, G., Rocha, G.M., Silva, J.L., Gomes, A.M.O., Envelope lipid-packing as a critical factor for the biological activity and stability of alphavirus particles isolated from mammalian and mosquito cells (2011) Journal of Biological Chemistry, 286, pp. 1730-1736 | ||
| 504 | |a Sun, X., Whittaker, G.R., Role for influenza virus envelope cholesterol in virus entry and infection (2003) Journal of Virology, 77, pp. 12543-12551 | ||
| 504 | |a Talarico, L.B., Damonte, E.B., Interference in dengue virus adsorption and uncoating by carrageenans (2007) Virology, 363, pp. 473-485 | ||
| 504 | |a Talarico, L.B., Pujol, C.A., Zibetti, R.G., Faria, P.C., Noseda, M.D., Duarte, M.E., Damonte, E.B., The antiviral activity of sulfated polysaccharides against dengue virus is dependent on virus serotype and host cell (2005) Antiviral Research, 66, pp. 103-110 | ||
| 504 | |a Thorp, E.B., Gallagher, T.M., Requirements for CEACAMs and cholesterol during murine coronavirus cell entry (2004) Journal of Virology, 78, pp. 2682-2692 | ||
| 504 | |a Umashankar, M., Sánchez-San Martín, C., Liao, M., Reilly, B., Guo, A., Taylor, G., Kielian, M., Differential cholesterol binding by class II fusion proteins determines membrane fusion properties (2008) Journal of Virology, 82, pp. 9245-9253 | ||
| 504 | |a Welsch, S., Miller, S., Romero-Bray, I., Merz, A., Bleck, C.K.E., Walther, P., Fuller, S.D., Bartenschlager, R., Composition and three-dimensional architecture of the dengue virus replication and assembly sites (2009) Cell Host & Microbe, 5, pp. 365-375 | ||
| 504 | |a Wu, L., Martin, T.D., Carrington, M., Kewal Ramani, V.N., Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission (2004) Virology, 318, pp. 17-23 | ||
| 504 | |a Yin, J., Glende, J., Schwegmann-Wessels, C., Enjuanes, L., Herrler, G., Ren, X., Cholesterol is important for a post-adsorption step in the entry process of transmissible gastroenteritis virus (2010) Antiviral Research, 88, pp. 311-316 | ||
| 504 | |a Zidovetzki, R., Levitan, I., Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies (2007) Biochimica et Biophysica Acta, 1768, pp. 1311-1324 | ||
| 520 | 3 | |a •Cholesterol in the virion envelope is essential for dengue virus infectivity.•The four dengue serotypes are similarly inactivated by cholesterol-extracting drugs.•Dengue virus uncoating is blocked in infection with cholesterol-depleted virions.•Virion treatment with exogenous cholesterol exert also a virucidal effect.•Cholesterol in the cell membranes is not required for dengue virus entry. The role of cholesterol in the virus envelope or in the cellular membranes for dengue virus (DENV) infection was examined by depletion with methyl-beta-cyclodextrin (MCD) or nystatin. Pretreatment of virions with MCD or nystatin significantly reduced virus infectivity in a dose-dependent manner. By contrast, pre-treatment of diverse human cell lines with MCD or nystatin did not affect DENV infection. The four DENV serotypes were similarly inactivated by cholesterol-extracting drugs and infectivity was partially rescued when virion suspensions were treated with MCD in the presence of bovine serum. The addition of serum or exogenous water-soluble cholesterol after MCD treatment did not produce a reversion of MCD inactivating effect. Furthermore, virion treatment with extra cholesterol exerted also a virucidal effect. Binding and uptake of cholesterol-deficient DENV into the host cell were not impaired, whereas the next step of fusion between virion envelope and endosome membrane leading to virion uncoating and release of nucleocapsids to the cytoplasm appeared to be prevented, as determined by the retention of capsid protein in cells infected with MCD inactivated-DENV virions. Thereafter, the infection was almost completely inhibited, given the failure of viral RNA synthesis and viral protein expression in cells infected with MCD-treated virions. These data suggest that envelope cholesterol is a critical factor in the fusion process for DENV entry. © 2013 Elsevier B.V. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica | ||
| 536 | |a Detalles de la financiación: Universidad de Buenos Aires | ||
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: We thank Dr. J. Aaskov (Univesity of Queensland, Australia) for the provision of antibodies against DENV-2 C protein, and Dr. J. Geffner for the provision of Raji/DC-SIGN + cells. We are grateful to Dr. Federico Fuentes and Jimena Martinez for help with confocal images and quantification. This work was funded by grants from Agencia Nacional para la Promoción Científica y Tecnológica (ANPCyT) , Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and Universidad de Buenos Aires, Argentina . EBD is member of the Research Career from CONICET and ACC is a fellow of the same institution. | ||
| 593 | |a Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IQUIBICEN-CONICET, Ciudad Universitaria, Pabellón 2, Piso 4, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CHOLESTEROL |
| 690 | 1 | 0 | |a DENGUE VIRUS |
| 690 | 1 | 0 | |a INFECTIVITY |
| 690 | 1 | 0 | |a METHYL-BETA-CYCLODEXTRIN |
| 690 | 1 | 0 | |a VIRAL ENVELOPE |
| 690 | 1 | 0 | |a VIRUCIDAL ACTIVITY |
| 690 | 1 | 0 | |a CAPSID PROTEIN |
| 690 | 1 | 0 | |a CHOLESTEROL |
| 690 | 1 | 0 | |a METHYL BETA CYCLODEXTRIN |
| 690 | 1 | 0 | |a NYSTATIN |
| 690 | 1 | 0 | |a PROTEIN |
| 690 | 1 | 0 | |a VIRUS PROTEIN |
| 690 | 1 | 0 | |a ANIMAL CELL |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CELL MEMBRANE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a CYTOPLASM |
| 690 | 1 | 0 | |a DENGUE |
| 690 | 1 | 0 | |a ENDOSOME |
| 690 | 1 | 0 | |a HOST CELL |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a RNA SYNTHESIS |
| 690 | 1 | 0 | |a SEROTYPE |
| 690 | 1 | 0 | |a VIRION |
| 690 | 1 | 0 | |a VIRUS ATTACHMENT |
| 690 | 1 | 0 | |a VIRUS ENVELOPE |
| 690 | 1 | 0 | |a VIRUS EXPRESSION |
| 690 | 1 | 0 | |a VIRUS INFECTIVITY |
| 690 | 1 | 0 | |a VIRUS NUCLEOCAPSID |
| 690 | 1 | 0 | |a CELL LINE |
| 690 | 1 | 0 | |a CHOLESTEROL |
| 690 | 1 | 0 | |a DENGUE VIRUS |
| 690 | 1 | 0 | |a HUMANS |
| 690 | 1 | 0 | |a MEMBRANE LIPIDS |
| 690 | 1 | 0 | |a VIRUS INTERNALIZATION |
| 690 | 1 | 0 | |a BOVINAE |
| 690 | 1 | 0 | |a DENGUE VIRUS |
| 690 | 1 | 0 | |a MIRIDAE |
| 650 | 1 | 7 | |2 spines |a VIRUS RNA |
| 700 | 1 | |a Damonte, E.B. | |
| 773 | 0 | |d 2013 |g v. 174 |h pp. 78-87 |k n. 1-2 |p Virus Res. |x 01681702 |w (AR-BaUEN)CENRE-7132 |t Virus Research | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877621671&doi=10.1016%2fj.virusres.2013.03.005&partnerID=40&md5=a4976894760fb5b6c40bca9552c7905b |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.virusres.2013.03.005 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_01681702_v174_n1-2_p78_Carro |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01681702_v174_n1-2_p78_Carro |y Registro en la Biblioteca Digital |
| 961 | |a paper_01681702_v174_n1-2_p78_Carro |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 72471 | ||