In vitro synthesis of a lipid-linked acetylated and pyruvilated olicosaccharide in Rhizobium trifolii

EDTA-treated Rhizobium trifolii cells (strain NA30) incorporate radioactivity from (14C) labeled UDP-Clc, UDP-ClcA, Acetyl-Coa and/or phosphoenol pyruvate into chloroform:methanol:water (1:2:0.3) extracts. The incorporation products have properties of prenyl-phospho-sugars; mild alkaline hydrolysis...

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Autor principal: Bossio, J.C
Otros Autores: Inon de Iannino, N., Dankert, M.A
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 1986
Acceso en línea:Registro en Scopus
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Registro en la Biblioteca Digital
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LEADER 06771caa a22008177a 4500
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008 190411s1986 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-0022648683 
024 7 |2 cas  |a acetic acid, 127-08-2, 127-09-3, 64-19-7, 71-50-1; lipid, 66455-18-3; pyruvic acid, 127-17-3, 19071-34-2, 57-60-3; Lipids; Oligosaccharides; Pyruvates; Pyruvic Acid, 127-17-3 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
030 |a BBRCA 
100 1 |a Bossio, J.C. 
245 1 3 |a In vitro synthesis of a lipid-linked acetylated and pyruvilated olicosaccharide in Rhizobium trifolii 
260 |c 1986 
270 1 0 |m Bossio, J.C.; Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales (UBA), 1405 Buenos Aires, Argentina 
506 |2 openaire  |e Política editorial 
504 |a Bauer, Infection of Legumes by Rhizobia (1981) Annual Review of Plant Physiology, 32, pp. 407-449 
504 |a Albersheim, Darvill, Davis, Lau, McNeil, Sharp, York, (1984) Structure, Function and Biosynthesis of Plant Cell Walls, pp. 19-51. , W.M. Dugger, S. Bartnicki-García 
504 |a Tolmasky, Staneloni, Ugalde, Leloir, (1980) Arch. Biochem. Biophys, 203, pp. 358-364 
504 |a Tolmasky, Staneloni, Leloir, (1982) J. Biol. Chem, 257, pp. 6751-6757 
504 |a Staneloni, Tolmasky, Leloir, (1984) J. Gen. Microbiol, 130, pp. 869-879 
504 |a Robertsen, Aman, Darvill, McNeil, Albersheim, Host-Symbiont Interactions : V. THE STRUCTURE OF ACIDIC EXTRACELLULAR POLYSACCHARIDES SECRETED BY RHIZOBIUM LEGUMINOSARUM AND RHIZOBIUM TRIFOLII (1981) PLANT PHYSIOLOGY, 67, pp. 389-400 
504 |a Couso, Ielpi, Dankert, (1980) Arch. Biochem. Biophys, 204, pp. 434-443 
504 |a García, Recondo, Dankert, Polysaccharide Biosynthesis in Acetobacter xylinum. Enzymatic Synthesis of Lipid Diphosphate and Monophospate Sugars (1974) European Journal of Biochemistry, 43, pp. 93-105 
504 |a Couso, Ielpi, García, Dankert, (1982) Eur. J. Biochem, 123, pp. 617-627 
504 |a Ielpi, Couso, Dankert, (1981) Biochem. Biophys. Res. Commun, 102, pp. 1400-1408 
504 |a Lowry, Rosebrough, Farr, Randall, (1951) J. Biol. Chem, 193, pp. 265-275 
504 |a Pont Lezica, R., Brett, C.T., Romero, P. and Dankert, M.A. Biochem. Biophys. Res. Commun. 66, 980-987; Trevelyan, Procter, Harrison, (1950) Nature (London), 166, pp. 444-445 
504 |a Amemura, Harada, (1983) Carbohydr. Res, 112, pp. 85-93 
504 |a Troy, Furman, Heath, (1971) J. Biol. Chem, 246, pp. 118-133 
504 |a Ielpi, Couso, Dankert, (1981) FEBS Lett, 130, pp. 253-256 
504 |a Ielpi, Couso, Dankert, (1983) Biochem. Internat, 6, pp. 323-333 
504 |a Chaudhari, Bishop, Dudman, (1973) Carbohydr. Res, 28, pp. 221-231 
504 |a Jansson, Lindberg, Ljunagren, (1979) Carbohydr. Res, 75, pp. 207-220 
520 3 |a EDTA-treated Rhizobium trifolii cells (strain NA30) incorporate radioactivity from (14C) labeled UDP-Clc, UDP-ClcA, Acetyl-Coa and/or phosphoenol pyruvate into chloroform:methanol:water (1:2:0.3) extracts. The incorporation products have properties of prenyl-phospho-sugars; mild alkaline hydrolysis of these extracts produce cyclic phosphate esters suggesting the presence of a diphosphate bridge, and mild acid or catalytic reduction-alkaline phosphatase treatments release four main componenets a, b, c and d, as judged by paper electrophoresis and chromatography and gel filtration studies. The four components can be obtained (14C)acetyl-labeled, but only compound c and to a lesser degree compound b can be (14C)pyruvate-labeled. For the exopolysaccharide produced by this strain the following repeating unit has been proposed (Robertsen et al. (1981), Plant Physiol. 67, 389-400): {A figure is presented}. The results obtained suggest that the octasaccharide repeating unit (compound a) with one (compound b) or two (compound c) ketal pyruvate residues are assembled on a lipid acceptor. All these compounds are assumed to be intermediates in the biosynthesis of R. trifolii exopolysaccharide. © 1986.  |l eng 
536 |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas, 435 
536 |a Detalles de la financiación: Facultad de Ciencias Físicas y Matemáticas 
536 |a Detalles de la financiación: Instituto de Investigaciones Biecas "Fundaci6n C-r", Facultad de Ciencias Exactas y Naturales (DBA) and Consejo National de Investigaciones Cientificas y T&nicas Patricias Argentinas 435, (1405) Buenos Aires, Argentina 
536 |a Detalles de la financiación: Am.-The authors are indebted to Dr I. Algranati and J.M. Olavarrla for critically reading this nmnuscript. They also thank the excellent technical assitance of Misses. Susana Raffo and Marta Bravo in the preparation of labeled sugar nucleotides. M.A.D. is a Career Investigator of the Consejo National de Investigaciones Cientlficas y T&nicas (Argentina). 
593 |a Instituto de Investigaciones Bioquímicas Fundación Campomar, Facultad de Ciencias Exactas y Naturales (UBA), 1405 Buenos Aires, Argentina 
593 |a Consejo Nacional de Investigaciones Cientificas y Técnicas Patricias Argentinas 435, 1405 Buenos Aires, Argentina 
690 1 0 |a ACETIC ACID 
690 1 0 |a LIPID 
690 1 0 |a OLIGOSACCHARIDE 
690 1 0 |a PYRUVIC ACID 
690 1 0 |a NONHUMAN 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a RHIZOBIUM TRIFOLII 
690 1 0 |a ACETYLATION 
690 1 0 |a CARBOHYDRATE SEQUENCE 
690 1 0 |a CHROMATOGRAPHY, GEL 
690 1 0 |a ELECTROPHORESIS, PAPER 
690 1 0 |a LIPIDS 
690 1 0 |a OLIGOSACCHARIDES 
690 1 0 |a PYRUVATES 
690 1 0 |a PYRUVIC ACID 
690 1 0 |a RHIZOBIUM 
690 1 0 |a SUPPORT, NON-U.S. GOV'T 
700 1 |a Inon de Iannino, N. 
700 1 |a Dankert, M.A. 
773 0 |d 1986  |g v. 134  |h pp. 205-211  |k n. 1  |p Biochem. Biophys. Res. Commun.  |x 0006291X  |w (AR-BaUEN)CENRE-905  |t Biochemical and Biophysical Research Communications 
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