Bioethics of somatic gene therapy : what do we know so far? [Separata] /

Objective: To provide a systematic overview of bioethical debate on somatic gene therapy as documented in the scientific literature. Methods: We performed a systematic review of reasons, following Strech and Sofaer approach, which is a method to systematically identify and classify arguments (reason...

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Detalles Bibliográficos
Autores principales: Buedo, Paola Estefanía (Autor), Bianchini, Alahí Dana (Autor), Klas, Katarzyna (Autor), Waligora, Marcin (Autor)
Autor Corporativo: FLACSO. Programa Argentina
Formato: Libro
Lenguaje:Inglés
Materias:
TERAPIA
TRATAMIENTO DE ENFERMEDADES
TERAPIA GENETICA
ENFERMEDADES GENETICAS
ETICA MEDICA
INVESTIGACION MEDICA
Acceso en línea:https://doi.org/10.1080/03007995.2023.2257600
Aporte de:Registro referencial: Solicitar el recurso aquí
Biblioteca Cs. Sociales E. Faletto (FLACSO) de FLACSO. Sede Académica Argentina
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100 |a Buedo, Paola Estefanía  |9 34894  |e aut. 
110 2 |a FLACSO. Programa Argentina  |9 110 
245 1 0 |a Bioethics of somatic gene therapy :  |b what do we know so far? [Separata] /   |c Paola Buedo, Alahi Bianchini, Katarzyna Klas & Marcin Waligora  |h DIG 
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520 |a Objective: To provide a systematic overview of bioethical debate on somatic gene therapy as documented in the scientific literature. Methods: We performed a systematic review of reasons, following Strech and Sofaer approach, which is a method to systematically identify and classify arguments (reasons) used in the scientific literature. We identified 217 eligible publications retrieved from PubMed, Lilacs, PhilPapers, and Google Scholar. A meta-synthesis was performed to analyze the data. Results: We extracted 189 arguments. Arguments were grouped into 23 categories. Twelve categories were classified as research-related, including the risk/benefit ratio, priorities and limits, informed consent, review, and monitoring. Eleven were classified as society-related, including population impact, human identity, public perception, human health. Conclusion: Our study provides a database of existing challenges and arguments of somatic gene therapy and may serve as the basis of normative analysis. By presenting collected arguments, we contribute to the discussion about the ethics and social dimensions of somatic gene therapy. 
650 4 |a TERAPIA  |9 32402 
650 4 |a TRATAMIENTO DE ENFERMEDADES  |9 10193 
650 4 |a TERAPIA GENETICA  |9 11049 
650 4 |a ENFERMEDADES GENETICAS  |9 10192 
650 4 |a ETICA MEDICA  |9 10121 
650 4 |a  INVESTIGACION MEDICA  |9 2776 
690 |a BIOETICA 
700 1 |a Bianchini, Alahí Dana  |9 33577  |e aut. 
700 1 |a Klas, Katarzyna  |9 38943  |e aut. 
700 1 |a Waligora, Marcin  |9 38944  |e aut. 
773 |d Reino Unido : Taylor and Francis , 2023  |t Current Medical Research and Opinion  |g Vol. 39 no. 10  |x 1473-4877 
856 |u https://doi.org/10.1080/03007995.2023.2257600 
942 |c ART 
999 |c 51507  |d 51507 

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