Becoming a selfish clan recombination associated to reverse - transcription in LTR retrotransposons

Transposable elements (TEs) are parasitic DNA bits capable of mobilization and mutagenesis, typically suppressed by host’s epigenetic silencing. Since the selfish DNA concept, it is appreciated that genomes are also molded by arms-races against natural TE inhabitants. However, our understanding of e...

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Autor principal: Drost, Hajk Georg
Otros Autores: Sánchez, Diego H.
Formato: Artículo
Lenguaje:Inglés
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Acceso en línea:http://ri.agro.uba.ar/files/download/articulo/2019drost.pdf
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Aporte de:Registro referencial: Solicitar el recurso aquí
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100 1 |9 70444  |a Drost, Hajk Georg  |u University of Cambridge. The Sainsbury Laboratory. United Kingdom. 
245 0 0 |a Becoming a selfish clan  |b recombination associated to reverse - transcription in LTR retrotransposons 
520 |a Transposable elements (TEs) are parasitic DNA bits capable of mobilization and mutagenesis, typically suppressed by host’s epigenetic silencing. Since the selfish DNA concept, it is appreciated that genomes are also molded by arms-races against natural TE inhabitants. However, our understanding of evolutionary processes shaping TEs adaptive populations is scarce. Here, we review the events of recombination associated toreverse-transcription in LTR retrotransposons, a process shuffling their genetic variants during replicative mobilization. Current evidence may suggest that recombinogenic retrotransposons could beneficially exploit host suppression, where clan behavior facilitates their speciation and diversification. Novel refinements to retrotransposons life-cycle and evolution models thus emerge. 
653 |a EPIGENETICS 
653 |a RECOMBINATION 
653 |a RETROELEMENTS 
653 |a REVERSE-TRANSCRIPTION 
653 |a LTR RETROTRANSPOSONS 
653 |a TRANSCRIPTIONAL GENE SILENCING 
653 |a TRANSPOSONS 
653 |a TRANSPOSABLE ELEMENTS 
700 1 |9 69714  |a Sánchez, Diego H.  |u Universidad de Buenos Aires. Facultad de Agronomía. Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura (IFEVA). Buenos Aires, Argentina.  |u CONICET – Universidad de Buenos Aires. Instituto de Investigaciones Fisiológicas y Ecológicas Vinculadas a la Agricultura (IFEVA). Buenos Aires, Argentina. 
773 |t Genome Biology and Evolution  |g Vol.11, no.12 (2019), p.3382–3392, grafs., il. 
856 |f 2019drost  |i en internet  |q application/pdf  |u http://ri.agro.uba.ar/files/download/articulo/2019drost.pdf  |x ARTI202003 
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