Longitudinal analysis of the effects of IGF1 - SnaBI genotypes on the growth curve of Angus bull calves

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The Insulin Growth Factor 1 [IGF1] has been proposed as a candidate gene for growth related traits as it plays a central role in growth and development of mammals. A relationship between serum IGF1 concentration and different growth traits in cattle has been documented. Furthermore, the IGF1-SnaBI S...

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Detalles Bibliográficos
Otros Autores: Rogberg Muñoz, Andrés, Cantet, Rodolfo Juan Carlos, Fernández, María Elena, Lirón, Juan Pedro, Prando, Alberto Juan, Birchmeier, Ana Nélida, Ripoli, María Verónica, Giovambattista, Guillermo
Formato: Artículo
Lenguaje:Inglés
Materias:
BULL CALVES
CATTLE
DNA
GROWTH
INSULIN GROWTH FACTOR 1
ANIMALIA
BOS
MAMMALIA
Acceso en línea:http://ri.agro.uba.ar/files/intranet/articulo/2013rogbergmunoz.pdf
LINK AL EDITOR
Aporte de:Registro referencial: Solicitar el recurso aquí
Biblioteca Central (FAUBA) de Universidad de Buenos Aires
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245 1 0 |a Longitudinal analysis of the effects of IGF1 - SnaBI genotypes on the growth curve of Angus bull calves 
520 |a The Insulin Growth Factor 1 [IGF1] has been proposed as a candidate gene for growth related traits as it plays a central role in growth and development of mammals. A relationship between serum IGF1 concentration and different growth traits in cattle has been documented. Furthermore, the IGF1-SnaBI SNP in the gene promoter region influences gene expression and IGF1 blood level. The current research was conducted to perform a genetic analysis of longitudinal data for growth curves through the evaluation of the influence of IGF1-SnaBI genotypes on the growth curve of beef cattle during highly anabolic stages. Data were taken on 275 Angus bull calves on two consecutive years, in two commercial cow-calf operations. Calves were weighed at birth, at weaning, and at 3 to 4 times before the year of age. A random regression animal model was employed for the analysis. Fixed effects were age of dam, herd-year, and age of calf [linear and quadratic terms nested within IGF1-SnaBI genotype]. Random effects were age at measure [linear and a quadratic terms nested within animal]. The analysis showed significant differences [P less than 0.01] in the growth curves at ages in between 66 and 291 days for the IGF1-SnaBI genotypes. At 210 days of age, the effect of substituting a T by a C was estimated to be 5.21. kg. These results suggest that the effect of IGF1-SnaBI over growth in cattle take place mostly before puberty. 
653 0 |a BULL CALVES 
653 0 |a CATTLE 
653 0 |a DNA 
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653 0 |a INSULIN GROWTH FACTOR 1 
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700 1 |a Ripoli, María Verónica  |9 72615 
700 1 |9 68263  |a Giovambattista, Guillermo 
773 |t Livestock Science  |g vol.154, no.1-3 (2013), p.55-59 
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900 |a ^aRogberg-Muñoz^bA. 
900 |a ^aCantet^bR.J.C. 
900 |a ^aFernández^bM.E. 
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900 |a ^aRogberg-Muñoz, A.^tInstituto de Genética Veterinaria (IGEVET), CCT La Plata - CONICET - Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
900 |a ^aRogberg-Muñoz, A.^tConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina 
900 |a ^aCantet, R.J.C.^tConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina 
900 |a ^aCantet, R.J.C.^tDepartamento de Producción Animal, Facultad de Agronomía, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina 
900 |a ^aFernández, M.E.^tInstituto de Genética Veterinaria (IGEVET), CCT La Plata - CONICET - Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
900 |a ^aLirón, J.P.^tInstituto de Genética Veterinaria (IGEVET), CCT La Plata - CONICET - Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
900 |a ^aPrando, A.^tDepartamento de Producción Animal, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
900 |a ^aBirchmeier, A.N.^tDepartamento de Producción Animal, Facultad de Agronomía, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina 
900 |a ^aRipoli, M.V.^tInstituto de Genética Veterinaria (IGEVET), CCT La Plata - CONICET - Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
900 |a ^aGiovambattista, G.^tInstituto de Genética Veterinaria (IGEVET), CCT La Plata - CONICET - Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina 
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900 |a BULL CALVES 
900 |a CATTLE 
900 |a DNA 
900 |a GROWTH 
900 |a INSULIN GROWTH FACTOR 1 
900 |a ANIMALIA 
900 |a BOS 
900 |a MAMMALIA 
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