Application of nutrigenomics in small ruminants lactation, growth, and beyond
Ruminants have a very special niche in the animal kingdom, and are the most important livestock species providing milk, meat, and wool for humans from consumption of highly-fibrous feedstuffs. Cattle, goat and sheep have been widely-used for years as models to study ruminal fermentation and the mech...
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Otros Autores: | , , , , |
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Formato: | Artículo |
Lenguaje: | Inglés |
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Acceso en línea: | http://ri.agro.uba.ar/files/intranet/articulo/2017osorio.pdf LINK AL EDITOR |
Aporte de: | Registro referencial: Solicitar el recurso aquí |
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022 | |a 0921-4488 | ||
024 | |a 10.1016/j.smallrumres.2017.06.021 | ||
040 | |a AR-BaUFA | ||
245 | 1 | |a Application of nutrigenomics in small ruminants |b lactation, growth, and beyond | |
520 | |a Ruminants have a very special niche in the animal kingdom, and are the most important livestock species providing milk, meat, and wool for humans from consumption of highly-fibrous feedstuffs. Cattle, goat and sheep have been widely-used for years as models to study ruminal fermentation and the mechanisms whereby tissues utilize nutrients for milk synthesis, growth, wool accretion, and reproduction. The advent of high-throughput technologies to study an animal's genome, proteome, and metabolome (i.e., “omics” tools) offered ruminant scientists the opportunity to study multiple levels of biological information to better understand the whole animal response to nutrition, environment, physiological state, and their interactions. The omics revolution gave rise to the field of nutrigenomics, i.e. the study of the genome-wide influences of nutrition through alteration in mRNA, protein, and metabolite expression or abundance. This field of research is relatively new in ruminants, and particularly sheep and goats. Dietary compounds affect gene expression directly or indirectly via interactions with transcription factors including ligand-dependent nuclear receptors. New knowledge generated through the application of functional analyses of transcriptomic, proteomic, and metabolomic data sets in goat and sheep is discussed. | ||
653 | |a NUTRITION | ||
653 | |a GENOMICS | ||
653 | |a LACTATION | ||
653 | |a BIOINFORMATICS | ||
653 | |a RUMINANT | ||
700 | 1 | |a Osorio, Johan S. |u Dairy and Food Science Department, South Dakota State University, 1111 College Ave, 113H Alfred Dairy Science Hall, Brookings, SD 57007, USA |9 67278 | |
700 | 1 | |a Vailati Riboni, Mario |u Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, 61801, USA |9 67279 | |
700 | 1 | |a Palladino, Alejandro |u Departamento de Producción Animal, Facultad de Agronomía, Universidad Buenos Aires, Av. San Martín 4453, 1417, Buenos Aires, Argentina |9 67281 | |
700 | 1 | |a Luo, Jun |u Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, PR China |9 67282 | |
700 | 1 | |a Loor, Juan J. |u Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL, 61801, USA. E-mail: jloor@illinois.edu |9 67283 | |
773 | 0 | |t Small Ruminant Research |g Vol.154 (2017), p.29-44, grafs., tbls. | |
856 | |f 2017osorio |i en reservorio |q application/pdf |u http://ri.agro.uba.ar/files/intranet/articulo/2017osorio.pdf |x ARTI201806 | ||
856 | |z LINK AL EDITOR |u http://www.elsevier.com | ||
942 | |c ARTICULO | ||
942 | |c ENLINEA | ||
976 | |a AAG |