Hormonal behavior correlates with follicular recruitment at mid - gestation in the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)
In mammals, hormonal regulation during gestation is crucial for embryo implantation and pregnancy success. This regulation is controlled through the level of progesterone (P4) that blocks the activity of the hypothalamic-hypophyseal-gonadal (HHG) axis. Previous studies in the pregnant South American...
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| Formato: | Artículo |
| Lenguaje: | Inglés |
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| Acceso en línea: | http://ri.agro.uba.ar/files/intranet/articulo/2017fraunhoffer.pdf LINK AL EDITOR |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 05792nab a22004337a 4500 | ||
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| 001 | 20180528112353.0 | ||
| 003 | AR-BaUFA | ||
| 005 | 20180629142050.0 | ||
| 008 | 180528t2017 xxu|||||o|||| 00| | eng d | ||
| 999 | |c 45531 |d 45531 | ||
| 999 | |d 45531 | ||
| 999 | |d 45531 | ||
| 999 | |d 45531 | ||
| 999 | |d 45531 | ||
| 999 | |d 45531 | ||
| 022 | |a 0016-6480 | ||
| 024 | |a 10.1016/j.ygcen.2017.06.010 | ||
| 040 | |a AR-BaUFA | ||
| 245 | 1 | |a Hormonal behavior correlates with follicular recruitment at mid - gestation in the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha) | |
| 520 | |a In mammals, hormonal regulation during gestation is crucial for embryo implantation and pregnancy success. This regulation is controlled through the level of progesterone (P4) that blocks the activity of the hypothalamic-hypophyseal-gonadal (HHG) axis. Previous studies in the pregnant South American plains vizcacha, Lagostomus maximus, have shown that the HHG axis activates around mid-gestation, promoting pre-ovulatory follicle formation. However, the characterization of the hormonal dynamics throughout gestation and its ovarian correlation has not been studied in depth. We studied the ovarian dynamics of L. maximus and its correlation with the hormonal profile during gestation, analyzing serum levels of P4, 17b-estradiol (E2), 4D androstenedione (A4), luteinizing hormone (LH) and follicle stimulating hormone (FSH) as well as the ovarian distribution and expression of their receptors. Additionally, we have analyzed the folliculogenesis and accessory corpora lutea (ACL) formation. P4 showed two concentration peaks reaching its highest level at mid-gestation decreasing at 91–100 days post coitum. P4 decrease is followed by an increase of circulating levels of A4, E2, FSH and LH and with an elevated number of antral/pre-ovulatory follicles which express PGR, ESR1, ESR2, AR, LHR and FSHR. In addition, ACL with oocyte retention and cytoplasmic lipid droplets in luteal cells were detected at this time point. These results show that in L. maximus the decrease of P4 level from mid-gestation enables follicular recruitment until pre-ovulatory stage and the development of functional ACL. | ||
| 653 | |a HORMONAL PROFILE | ||
| 653 | |a PREGNANCY | ||
| 653 | |a LAGOSTOMUS MAXIMUS | ||
| 653 | |a OVARIAN DYNAMICS | ||
| 700 | 1 | |a Fraunhoffer, Nicolas Alejandro |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina. E-mail: fraunhoffer.nicolas@maimonides.edu |9 67213 | |
| 700 | 1 | |a Jensen, Federico |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina; Centro de Estudios Farmacológicos y Botánicos, CEFYBOCONICET, Buenos Aires, Argentina. |9 67214 | |
| 700 | 1 | |a Leopardo, Noelia |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina |9 67215 | |
| 700 | 1 | |a Inserra, Pablo Ignacio Felipe |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina |9 67216 | |
| 700 | 1 | |a Meilerman Abuelafia, Analía |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina |9 67217 | |
| 700 | 1 | |a Espinosa, María Beatriz |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina; Instituto de Investigaciones en Biociencias Agrícolas y Ambientales, INBA-CONICET, Facultad de Agronomía, Universidad de Buenos Aires, Argentina. |9 67218 | |
| 700 | 1 | |a Charif, Santiago Elías |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina |9 67219 | |
| 700 | 1 | |a Dorfman, Verónica Berta |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina |9 67220 | |
| 700 | 1 | |a Vitullo, Alfredo Daniel |u Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina. E-mail: vitullo.alfredo@maimonides.edu |9 67221 | |
| 773 | |t General and Comparative Endocrinology |g Vol.250 (2017), p.162-174, grafs., fot., tbls. | ||
| 856 | |f 2017fraunhoffer |i en reservorio |q application/pdf |u http://ri.agro.uba.ar/files/intranet/articulo/2017fraunhoffer.pdf |x ARTI201806 | ||
| 856 | |z LINK AL EDITOR |u http://www.elsevier.com | ||
| 942 | |c ARTICULO | ||
| 942 | |c ENLINEA | ||
| 976 | |a AAG | ||