2 (2 amino 3 methoxyphenyl)chromone 4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole Apoptosis Catalase Cell Line DNA Enzyme Activation Humans Hydrogen Peroxide Mitogen-Activated Protein Kinases Oxidants Phosphorylation Transcription Factor AP-1 Zinc anthra[1,9 cd]pyrazol 6(2h) one apoptosis article binding affinity catalase cell proliferation concentration response controlled study enzyme regulation gene expression regulation human human cell hydrogen peroxide incubation time mitogen activated protein kinase mitogen activated protein kinase 1