Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549

por Silva, I.T., Geller, F.C., Persich, L., Dudek, S.E., Lang, K.L., Caro, M.S.B., Durán, F.J., Schenkel, E.P., Ludwig, S., Simões, C.M.O.

Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn

por Silva, I.T., Teixeira, C.R., Lang, K.L., da Guimaraes, T.R., Dudek, S.E., Durán, F.J., Ludwig, S., Caro, M.S.B., Schenkel, E.P., Simões, C.M.O.

Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol

por Lang, K.L., Silva, I.T., Zimmermann, L.A., Lhullier, C., Arana, M.V.M., Palermo, J.A., Falkenberg, M., Simões, C.M.O., Schenkel, E.P., Durán, F.J.

Polyoxygenated steroids from the octocoral leptogorgia punicea and in vitro evaluation of their cytotoxic activity

por Moritz, M.I.G., Marostica, L.L., Bianco, É.M., Almeida, M.T.R., Carraro, J.L., Cabrera, G.M., Palermo, J.A., Simões, C.M.O., Schenkel, E.P.

Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549

por Marostica, L.L., Silva, I.T., Kratz, J.M., Persich, L., Geller, F.C., Lang, K.L., Caro, M.S.B., Durán, F.J., Schenkel, E.P., Simões, C.M.O.

Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line

por Lang, K.L., Silva, I.T., Machado, V.R., Zimmermann, L.A., Caro, M.S.B., Simões, C.M.O., Schenkel, E.P., Durán, F.J., Bernardes, L.S.C., De Melo, E.B.

In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B

por Silva, I.T., Carvalho, A., Lang, K.L., Dudek, S.E., Masemann, D., Durán, F.J., Caro, M.S.B., Rapp, U.R., Wixler, V., Schenkel, E.P., Simões, C.M.O., Ludwig, S.

Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity

por Oliveira, S.Q.D., Almeida, M.T.R.D., Maraslis, F., Silva, I.T., Sincero, T.C.M., Palermo, J.A., Cabrera, G.M., Caro, M.S.B., Simões, C.M.O., Schenkel, E.P.

New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn

por Lang, K.L., Da Rosa Guimarães, T., Rocha MacHado, V., Zimmermann, L.A., Silva, I.T., Teixeira, M.R., Durán, F.J., Palermo, J.A., Simões, C.M.O., Caro, M.S.B., Schenkel, E.P.

Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model

por Marostica, L.L., de Barros, A.L.B., Oliveira, J., Salgado, B.S., Cassali, G.D., Leite, E.A., Cardoso, V.N., Lang, K.L., Caro, M.S.B., Durán, F.J., Schenkel, E.P., de Oliveira, M.C., Simões, C.M.O.

Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives

por Lang, K.L., Silva, I.T., Zimmermann, L.A., MacHado, V.R., Teixeira, M.R., Lapuh, M.I., Galetti, M.A., Palermo, J.A., Cabrera, G.M., Bernardes, L.S.C., Simões, C.M.O., Schenkel, E.P., Caro, M.S.B., Durán, F.J.

Anti HSV-1 activity of halistanol sulfate and halistanol sulfate C isolated from Brazilian marine sponge Petromica citrina (Demospongiae)

por Guimarães, T.D.R., Quiroz, C.G., Rigotto, C., De Oliveira, S.Q., De Almeida, M.T.R., Bianco, É.M., Moritz, M.I.G., Carraro, J.L., Palermo, J.A., Cabrera, G., Schenkel, E.P., Reginatto, F.H., Simões, C.M.O.