Animals Anti-Inflammatory Agents, Non-Steroidal Antigen Presentation Antioxidants Cells, Cultured Curcumin Dendritic Cells Dendritic cells Diabetes Mellitus, Experimental Diabetes Mellitus, Type 1 Disease Models, Animal Humans Inflammation Interferon-gamma Lymphocyte Activation Mice Mice, Inbred BALB C Mice, Inbred NOD Mice, SCID Mice, Transgenic NF-kappa B NOD SCID mouse NOD mouse T lymphocyte T lymphocyte activation T lymphocyte receptor T lymphocytes T-Box Domain Proteins T-bet Th1 Cells