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article 2,826 nonhuman 2,622 controlled study 2,151 priority journal 2,043 Animals 1,712 enzyme activity 1,363 unclassified drug 1,282 human 1,150 Humans 1,016 metabolism 914 animal cell 897 animal experiment 773 mouse 710 animal 682 POLITICAL ACTIVITY 640 Mice 639 Article 635 male 630 human cell 628 protein expression 624 animal tissue 584 female 580 Female 543 signal transduction 532 Male 530 chemistry 437 animal model 426 rat 420 enzyme activation 413 in vitro study 404