complex formation article 188 priority journal 118 unclassified drug 86 nonhuman 80 controlled study 76 Humans 58 Animals 56 human 48 protein protein interaction 38 Protein Binding 34 binding site 34 chemistry 34 protein binding 34 binding affinity 32 metabolism 32 pH 32 molecular dynamics 30 protein domain 30 protein function 28 synthesis 28 Binding Sites 26 Mice 26 chemical structure 26 crystal structure 26 heat shock protein 90 26 mouse 26 signal transduction 26 enzyme activity 24 infrared spectroscopy 24