catabolism article 8 nonhuman 8 controlled study 6 enzyme activity 6 oxidation 6 oxidative stress 6 priority journal 6 protein degradation 6 unclassified drug 6 (20) 3beta,16beta dihydroxy 5 pregnen 20,16 carbolactone 4 3beta hydroxy 5 androsterone 4 Animalia 4 Bacteria (microorganisms) 4 Mutation 4 Oxidation-Reduction 4 alkaloid derivative 4 amidase 4 androsterone 4 bacterial strain 4 biodegradation 4 cis isomer 4 conference paper 4 correlation analysis 4 diosgenin 4 extraction 4 fruit 4 human 4 hydroxyl group 4 lactone 4