article binding affinity 174 priority journal 124 nonhuman 112 controlled study 98 unclassified drug 76 Animals 64 Protein Binding 52 Humans 50 human 48 binding site 42 protein binding 40 Models, Molecular 38 Molecular Sequence Data 36 Kinetics 28 enzyme activity 28 metabolism 28 molecular dynamics 28 Amino Acid Sequence 26 Binding Sites 26 Male 26 animal cell 26 carboxy terminal sequence 26 complex formation 26 conformational transition 26 DNA 24 rat 24 Proteins 22 Rats 22 animal tissue 22