article human 210 human cell signal transduction 178 controlled study 174 priority journal 160 Humans 150 Signal Transduction 90 protein expression 90 nonhuman 76 Animals 64 animal cell 60 metabolism 58 protein phosphorylation 52 unclassified drug 52 phosphatidylinositol 3 kinase 50 Cell Line, Tumor 48 Mice 48 mouse 48 Female 46 cell proliferation 46 enzyme activation 44 Phosphorylation 42 mitogen activated protein kinase 42 Cell Line 40 enzyme activity 40 protein function 40 Western blotting 38 apoptosis 38 female 38