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addition reaction article 14 reaction analysis 12 unclassified drug 9 chirality 6 reagent 6 substitution reaction 6 Animals 4 Grignard reaction 4 Molecular Structure 4 aldehyde 4 analytic method 4 catalysis 4 chemical reaction 4 chemical structure 4 complex formation 4 conference paper 4 controlled study 4 electricity 4 electrochemistry 4 enantiomer 4 enantioselectivity 4 kinetics 4 lithiation 4 nitroprusside sodium 4 nonhuman 4 structure analysis 4 synthesis 4 drug synthesis 3 1 chloro 2,4 dinitrobenzene 2