Alternative splicing 4 Chromatin 4 Co-transcriptional splicing 4 Kinetic model 4 RNA polymerase II 4 RNA polymerase II-CTD 4 Transcription-splicing coupling alternative RNA splicing 4 article 4 chromatin structure 4 genetic transcription 4 human 4 intron 4 priority journal 4 transcription regulation 4 Alternative Splicing 2 Humans 2 RNA Polymerase II 2 RNA Precursors 2 RNA Splicing 2 RNA precursor 2 RNA splicing 2 RNA transcription 2 RNA translation 2 Transcription, Genetic 2 cancer genetics 2 carboxy terminal sequence 2 carcinogenesis 2 chemical reaction kinetics 2 chromatin 2