Algorithms 4 Buffers 4 Calcium 4 Calcium Signaling 4 Cell Membrane 4 Computer Simulation 4 Cytosol 4 Dose-Response Relationship, Drug 4 Endoplasmic Reticulum 4 High resolution Inositol 1,4,5-Trisphosphate 4 Ion Channel Gating 4 Kinetics 4 Local signal 4 Models, Biological 4 Models, Statistical 4 Optical experiments 4 Physiological process 4 Probability 4 Puffs Sugars 4 Transport properties 4 algorithm 4 article 4 biological model 4 buffer 4 calcium 4 calcium signaling 4 cell membrane 4 channel gating 4