Animals animal tissue male nonhuman 522 controlled study 451 Male 435 priority journal 393 article 392 animal experiment 376 mouse 221 Mice 214 female 200 animal 190 animal cell 181 animal model 169 Female 149 rat 139 metabolism 136 Article 132 Rats 130 protein expression 120 physiology 112 unclassified drug 90 enzyme activity 85 Animalia 79 Rats, Sprague-Dawley 77 messenger RNA 77 immunohistochemistry 74 adult 67 drug effects 67