Bridging Theory and Experiment to Address Structural Properties of Truncated Haemoglobins: Insights from Thermobifida fusca HbO

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In this chapter, we will discuss the paradigmatic case of Thermobifida fusca (Tf-trHb) HbO in its ferrous and ferric states and its behaviour towards a battery of possible ligands. This choice was dictated by the fact that it has been one of the most extensively studied truncated haemoglobins, both...

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Detalles Bibliográficos
Autores principales: Howes, B.D., Boechi, L., Boffi, A., Estrin, D.E., Smulevich, G.
Formato: CHAP
Materias:
Computer simulation
Distal residues
Exogenous ligand binding
H-bond
Ligand affinity
Ligand recognition
Molecular dynamics simulation
Resonance Raman
Spectroscopy
Truncated haemoglobins
bacterial protein
hemoglobin
protein binding
Actinobacteria
chemistry
enzyme active site
enzymology
metabolism
Bacterial Proteins
Catalytic Domain
Hemoglobins
Protein Binding
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_21625468_v67_n_p85_Howes
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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