Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses

Spontaneous electrical activity generated by developing sensory cells and neurons is crucial for the maturation of neural circuits. The full maturation of mammalian auditory inner hair cells (IHCs) depends on patterns of spontaneous action potentials during a 'critical period' of developme...

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Detalles Bibliográficos
Autores principales: Johnson, S.L., Wedemeyer, C., Vetter, D.E., Adachi, R., Holley, M.C., Elgoyhen, A.B., Marcotti, W.
Formato: JOUR
Materias:
Calcium current
Cochlea
Development
Efferent system
Exocytosis
Hair cell
Chrna9 protein, mouse
nicotinic receptor
synaptotagmin II
Syt2 protein, mouse
action potential
animal
article
cochlea
genetics
hair cell
knockout mouse
motoneuron
mouse
physiology
stereocilium
synapse
synaptic transmission
Action Potentials
Animals
Hair Cells, Auditory, Inner
Mice
Mice, Knockout
Motor Neurons
Receptors, Nicotinic
Stereocilia
Synapses
Synaptic Transmission
Synaptotagmin II
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_20462441_v3_nNOV_p_Johnson
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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