Ligand uptake in Mycobacterium tuberculosis truncated hemoglobins is controlled by both internal tunnels and active site water molecules
Mycobacterium tuberculosis, the causative agent of human tuberculosis, has two proteins belonging to the truncated hemoglobin (trHb) family. Mt-trHbN presents well-defined internal hydrophobic tunnels that allow O 2 and •NO to migrate easily from the solvent to the active site, whereas Mt-trHbO poss...
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| Autores principales: | Boechi, L., Boron, I., Bustamante, J.P., Davidge, K.S., Singh, S., Bowman, L.A.H., Tinajero-Trejo, M., Carballal, S., Radi, R., Poole, R.K., Dikshit, K., Estrin, D.A., Marti, M.A. |
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| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_20461402_v4_n_p_Boechi |
| Aporte de: |
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