The IL-17A rs2275913 single nucleotide polymorphism is associated with protection to tuberculosis but related to higher disease severity in Argentina

Mycobacterium tuberculosis (Mtb) causes nearly 10 millions of new tuberculosis disease cases annually. However, most individuals exposed to Mtb do not develop tuberculosis, suggesting the influence of a human genetic component. Here, we investigated the association of the rs2275913 SNP (G → A) from...

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Detalles Bibliográficos
Autores principales: Rolandelli, A., Del Pino, R.E.H., Pellegrini, J.M., Tateosian, N.L., Amiano, N.O., De La Barrera, S., Casco, N., Gutiérrez, M., Palmero, D.J., García, V.E.
Formato: JOUR
Materias:
gamma interferon
IL17A protein, human
interleukin 17
adult
allele
Argentina
blood
female
gene frequency
genetic predisposition
genetics
genotype
human
male
middle aged
severity of illness index
single nucleotide polymorphism
tuberculosis
Adult
Alleles
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Interferon-gamma
Interleukin-17
Male
Middle Aged
Polymorphism, Single Nucleotide
Severity of Illness Index
Tuberculosis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_20452322_v7_n_p_Rolandelli
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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