Tertiary and quaternary structural basis of oxygen affinity in human hemoglobin as revealed by multiscale simulations

Human hemoglobin (Hb) is a benchmark protein of structural biology that shaped our view of allosterism over 60 years ago, with the introduction of the MWC model based on Perutz structures of the oxy(R) and deoxy(T) states and the more recent Tertiary Two-State model that proposed the existence of in...

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Detalles Bibliográficos
Autores principales:	Bringas, M., Petruk, A.A., Estrin, D.A., Capece, L., Martí, M.A.
Formato:	JOUR
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_20452322_v7_n1_p_Bringas
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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