Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease

The human transcriptome comprises a myriad of non protein-coding RNA species, including long noncoding RNAs (lncRNAs), which have a remarkable role in transcriptional and epigenetic regulation. We hypothesized that variants in lncRNAs influence the susceptibility to nonalcoholic fatty liver disease...

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Detalles Bibliográficos
Autores principales: Sookoian, S., Rohr, C., Salatino, A., Dopazo, H., Gianotti, T.F., Castaño, G.O., Pirola, C.J.
Formato: JOUR
Materias:
Epigenetics
Gene expression
LncRNAs
NAFLD
Nonalcoholic steatohepatitis
CCAAT enhancer binding protein beta
glucose
insulin
long untranslated RNA
microRNA
transcription factor JunD
transcription factor MafK
adult
Article
body mass
case control study
controlled study
disease severity
female
genetic risk
genetic susceptibility
genetic variation
homozygosity
human
insulin resistance
major clinical study
male
next generation sequencing
nonalcoholic fatty liver
oncogene
replication study
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19492553_v8_n14_p22917_Sookoian
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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