Broad MICA/B Expression in the Small Bowel Mucosa: A Link between Cellular Stress and Celiac Disease

The MICA/B genes (MHC class I chain related genes A and B) encode for non conventional class I HLA molecules which have no role in antigen presentation. MICA/B are up-regulated by different stress conditions such as heat-shock, oxidative stress, neoplasic transformation and viral infection. Particul...

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Detalles Bibliográficos
Autores principales: Allegretti, Y.L., Bondar, C., Guzman, L., Cueto Rua, E., Chopita, N., Fuertes, M., Zwirner, N.W., Chirdo, F.G.
Formato: JOUR
Materias:
CD20 antigen
CD3 antigen
CD68 antigen
CD7 antigen
glycoprotein p 15095
major histocompatibility antigen class 1
major histocompatibility antigen class 2
syndecan 1
article
B lymphocyte
celiac disease
cell stress
cellular distribution
child
clinical article
confocal microscopy
controlled study
disease severity
endoplasmic reticulum stress
flow cytometry
gene
gene expression regulation
human
human cell
human tissue
immune dysregulation
immunofluorescence test
immunopathogenesis
intestine biopsy
lamina propria
macrophage
MICA gene
MICAB gene
oxidative stress
preschool child
protein localization
small intestine mucosa
B-Lymphocytes
Celiac Disease
Child, Preschool
Duodenum
Enterocytes
Female
Gene Expression
Histocompatibility Antigens Class I
Humans
Intestinal Mucosa
Macrophages
Male
Plasma Cells
Severity of Illness Index
Stress, Physiological
T-Lymphocytes
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v8_n9_p_Allegretti
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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