An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae

Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for diphtheria infection and once regarded for high mortalities worldwide. The fatality gradually decreased with improved living standards and further alleviated when many immunization programs were introduced. However, n...

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Detalles Bibliográficos
Autores principales: Jamal, S.B., Hassan, S.S., Tiwari, S., Viana, M.V., De Jesus Benevides, L., Ullah, A., Turjanski, A.G., Barh, D., Ghosh, P., Costa, D.A., Silva, A., Röttger, R., Baumbach, J., Azevedo, V.A.C.
Formato: JOUR
Materias:
bacterial protein
protein bioB
protein DIP0983
protein DIP1084
protein glpX
protein hisE
protein nusB
protein rpsH
protein smpB
unclassified drug
antiinfective agent
bacterial vaccine
ligand
Article
bacterial genome
bacterial strain
bacterium identification
computer model
controlled study
Corynebacterium diphtheriae
gene identification
molecular docking
nonhuman
protein analysis
protein function
protein protein interaction
protein structure
proteomics
biological model
computer simulation
drug effects
genetics
human
metabolism
pathogenicity
validation study
Anti-Bacterial Agents
Bacterial Proteins
Bacterial Vaccines
Computer Simulation
Genome, Bacterial
Humans
Ligands
Models, Biological
Molecular Docking Simulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v12_n10_p_Jamal
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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