Uncovering distinct protein-network topologies in heterogeneous cell populations

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Background: Cell biology research is fundamentally limited by the number of intracellular components, particularly proteins, that can be co-measured in the same cell. Therefore, cell-to-cell heterogeneity in unmeasured proteins can lead to completely different observed relations between the same mea...

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Detalles Bibliográficos
Autores principales: Wieczorek, J., Malik-Sheriff, R.S., Fermin, Y., Grecco, H.E., Zamir, E., Ickstadt, K.
Formato: INPR
Materias:
Bayesian analysis
Cluster analysis
Intercellular variability
Network analysis
Protein networks
Reverse engineering
Unmixing
epidermal growth factor
mitogen activated protein kinase
nerve growth factor
Raf protein
animal
Bayes theorem
biological model
biology
drug effects
metabolism
PC12 cell line
procedures
protein protein interaction
rat
Animals
Bayes Theorem
Computational Biology
Epidermal Growth Factor
Mitogen-Activated Protein Kinases
Models, Biological
Nerve Growth Factor
PC12 Cells
Protein Interaction Maps
raf Kinases
Rats
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_17520509_v_n_p_Wieczorek
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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