Primary immunodeficiencies unravel the role of IL-2/CD25/STAT5b in human natural killer cell maturation

Natural killer (NK) cells play a pivotal role during immunity against viruses and circumstantial evidence also indicates that they can protect the host against developing tumors. Peripheral blood NK cells comprise CD56brightCD16lo/- cells that constitutively express CD25 (IL-2Ra) and CD56dimCD16hi c...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Caldirola, M.S., Broggi, M.G.R., Gaillard, M.I., Bezrodnik, L., Zwirner, N.W.
Formato:	JOUR
Materias:	CD25 IL-2 Natural killer cells Primary immunodeficiencies STAT5b CD16 antigen CD3 antigen CD56 antigen chemokine receptor CCR7 gamma interferon granzyme B interleukin 15 interleukin 2 interleukin 2 receptor alpha L selectin monoclonal antibody nerve cell adhesion molecule perforin STAT5b protein Article atopic dermatitis autoimmune thyroiditis case report cell count cell maturation cell proliferation assay chronic diarrhea clinical article controlled study cytokine production degranulation assay down regulation eczema female flow cytometry growth disorder human human cell immune deficiency immunohistochemistry lower respiratory tract infection natural killer cell peripheral blood mononuclear cell phenotype pneumonia protein expression signal transduction upregulation
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_16643224_v9_nJUN_p_Caldirola
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Primary immunodeficiencies unravel the role of IL-2/CD25/STAT5b in human natural killer cell maturation
Publicado: (2018)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.
Publicado: (2012)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, C.I., et al.
Publicado: (2012)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
por: Domaica, Carolina Inés, et al.
Publicado: (2012)

Differential migration and activation profile of monocytes after trophoblast interaction
Publicado: (2014)

Differential migration and activation profile of monocytes after trophoblast interaction
por: Grasso, E., et al.

Interleukin (IL)-23 stimulates IFN-γ secretion by CD56bright natural killer cells and enhances IL-18-driven dendritic cells activation
por: Ziblat, A., et al.

Interleukin (IL)-23 stimulates IFN-γ secretion by CD56bright natural killer cells and enhances IL-18-driven dendritic cells activation
Publicado: (2018)

Integrating the universe of regulatory cells in cancer. A major hurdle for successful immunotherapy
por: Ilarregui, J.M., et al.

Integrating the universe of regulatory cells in cancer. A major hurdle for successful immunotherapy
Publicado: (2007)

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness
por: Ziblat, A., et al.

IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness
por: Ziblat, Andrea, et al.
Publicado: (2015)

Regulatory dendritic cells restrain NK cell IFN-γ production through mechanisms involving NKp46, IL-10, and MHC class I-specific inhibitory receptors
por: Spallanzani, R.G., et al.

Regulatory dendritic cells restrain NK cell IFN-γ production through mechanisms involving NKp46, IL-10, and MHC class I-specific inhibitory receptors
por: Ziblat, Andrea, et al.
Publicado: (2015)

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.
Publicado: (2007)

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, E.M., et al.
Publicado: (2007)

Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j
por: Nuñez, S.Y., et al.

Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j
Publicado: (2018)

Monocyte-derived dendritic cells loaded with a mixture of apoptotic/ necrotic melanoma cells efficiently cross-present gp100 and MART-1 antigens to specific CD8+ T lymphocytes
por: von Euw, Erika María, et al.
Publicado: (2007)

Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: The case of IL-27
por: Ziblat, Andrea
Publicado: (2017)

Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: The case of IL-27
por: Zwirner, N.W., et al.

Dendritic Cells Exposed to Triiodothyronine Deliver Pro-Inflammatory Signals and Amplify IL-17-Driven Immune Responses
por: Alamino, V.A., et al.

Dendritic Cells Exposed to Triiodothyronine Deliver Pro-Inflammatory Signals and Amplify IL-17-Driven Immune Responses
Publicado: (2019)

Mesenchymal stem cells and their use in therapy: What has been achieved?
por: Fernández Vallone, V.B., et al.

Anti-melanoma vaccinal capacity of CD11c-positive and -negative cell populations present in GM-CSF cultures derived from murine bone marrow precursors
por: Campisano, S., et al.

Mesenchymal stem cells and their use in therapy: What has been achieved?
Publicado: (2013)

Control of dendritic cell maturation and function by triiodothyronine
por: Mascanfroni, I., et al.

CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis
por: Fernández Do Porto, D.A., et al.

Anti-melanoma vaccinal capacity of CD11c-positive and -negative cell populations present in GM-CSF cultures derived from murine bone marrow precursors
por: Gazzaniga, Silvina N.
Publicado: (2013)

CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis
Publicado: (2012)

Lymphocyte subsets and cytokines in adenoviral infection in children
Publicado: (1998)

Lymphocyte subsets and cytokines in adenoviral infection in children
por: Mistchenko, A.S., et al.

Control of dendritic cell maturation and function by triiodothyronine
por: Ilarregui, Juan Martín
Publicado: (2008)

CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C viruscoinfected patients
por: Laufer, N., et al.

CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C viruscoinfected patients
Publicado: (2017)

IFN-γ production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB
por: Pasquinelli, V., et al.

IFN-γ production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB
Publicado: (2009)

Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling
Publicado: (2016)