Cell cycle inhibitor, p19INK4d, promotes cell survival and decreases chromosomal aberrations after genotoxic insult due to enhanced DNA repair

Genome integrity and cell proliferation and survival are regulated by an intricate network of pathways that includes cell cycle checkpoints, DNA repair and recombination, and programmed cell death. It makes sense that there should be a coordinated regulation of these different processes, but the com...

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Detalles Bibliográficos
Autores principales:	Scassa, M.E., Marazita, M.C., Ceruti, J.M., Carcagno, A.L., Sirkin, P.F., González-Cid, M., Pignataro, O.P., Cánepa, E.T.
Formato:	JOUR
Materias:	Apoptosis Cell survival Chromosomal aberrations DNA repair Genotoxic p19INK4d complementary DNA cyclin dependent kinase inhibitor 2D phosphorus 32 RNA animal cell article cell cycle cell growth cell viability chromosome aberration clonogenic assay controlled study DNA damage DNA recombination DNA synthesis flow cytometry genotoxicity growth inhibition isotope labeling mouse nonhuman Northern blotting polyacrylamide gel electrophoresis priority journal protein content tumor cell culture ultraviolet irradiation Western blotting Animals Blotting, Northern Blotting, Western Cell Survival Chromosome Aberrations Colony-Forming Units Assay Cyclin-Dependent Kinase Inhibitor p19 DNA Damage DNA Repair Genomic Instability Humans Immunoprecipitation Mice Pyrimidine Dimers Radiation Tolerance RNA, Messenger Thymidine Ultraviolet Rays
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_15687864_v6_n5_p626_Scassa
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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