Ryanodine is a positive modulator of acetylcholine receptor gating in cochlear hair cells

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The efferent synaptic specialization of hair cells includes a near-membrane synaptic cistern, whose presence suggests a role for internal calcium stores in cholinergic inhibition. Calcium release channels from internal stores include 'ryanodine receptors', whose participation is usually de...

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Detalles Bibliográficos
Autores principales: Zorrilla De San Martín, J., Ballestero, J., Katz, E., Elgoyhen, A.B., Fuchs, P.A.
Formato: JOUR
Materias:
α9α10 receptors
Acetylcholine
Efferent system
Ion channels
Nicotinic receptors
Ryanodine
acetylcholine
alkaloid
calcium
calcium channel
cholinergic receptor
nicotinic acetylcholine receptor alpha10
nicotinic acetylcholine receptor alpha9
potassium channel
ryanodine
unclassified drug
animal cell
article
calcium transport
cell specificity
channel gating
cholinergic system
cochlea
controlled study
facilitation
gene expression
hair cell
membrane current
mouse
nerve cell plasticity
nonhuman
oocyte
priority journal
receptor affinity
Xenopus
Xenopus laevis
Animals
Chickens
Dose-Response Relationship, Drug
Hair Cells, Auditory
Ion Channel Gating
Mice
Potassium Channels, Calcium-Activated
Protein Subunits
Rats
Receptors, Cholinergic
Receptors, Nicotinic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15253961_v8_n4_p474_ZorrillaDeSanMartin
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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