Unveiling the association of STAT3 and HO-1 in prostate cancer: Role beyond heme degradation

Activation of the androgen receptor (AR) is a key step in the development of prostate cancer (PCa). Several mechanisms have been identified in AR activation, among them signal transducer and activator of transcription 3 (STAT3) signaling. Disruption of STAT3 activity has been associated to cancer pr...

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Detalles Bibliográficos
Autores principales: Elguero, B., Gueron, G., Giudice, J., Toscani, M.A., de Luca, P., Zalazar, F., Coluccio-Leskow, F., Meiss, R., Navone, N., de Siervi, A., Vazquez, E.
Formato: JOUR
Materias:
androgen receptor
cyclin D1
heme oxygenase 1
hemin
interleukin 6
messenger RNA
prostate specific antigen
protein bcl xl
STAT3 protein
survivin
testosterone
animal experiment
animal model
animal tissue
article
cellular distribution
chromatin immunoprecipitation
confocal laser microscopy
confocal microscopy
controlled study
gene overexpression
human
human cell
immunocytochemistry
immunofluorescence test
immunohistochemistry
immunoreactivity
molecular interaction
mouse
nonhuman
priority journal
promoter region
prostate cancer
protein expression
protein localization
protein synthesis regulation
real time polymerase chain reaction
reverse transcription polymerase chain reaction
signal transduction
Western blotting
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15228002_v14_n11_p1043_Elguero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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