Capturing coevolutionary signals inrepeat proteins

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Background: The analysis of correlations of amino acid occurrences in globular domains has led to the development of statistical tools that can identify native contacts - portions of the chains that come to close distance in folded structural ensembles. Here we introduce a direct coupling analysis f...

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Detalles Bibliográficos
Autores principales: Espada, R., Parra, R.G., Mora, T., Walczak, A.M., Ferreiro, D.U.
Formato: JOUR
Materias:
Co-evolution
Direct coupling analysis
Direct information
Repeat proteins
Amino acids
Statistical mechanics
Confidence levels
Direct coupling
Evolutionary information
Pair correlations
Translational symmetry
Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14712105_v16_n1_p1_Espada
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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