A fluorescence nanoscopy marker for corticotropin-releasing hormone type 1 receptor: Computer design, synthesis, signaling effects, super-resolved fluorescence imaging, and: In situ affinity constant in cells

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Class B G protein-coupled receptors (GPCRs) are involved in a variety of human pathophysiological states. These groups of membrane receptors are less studied than class A GPCRs due to the lack of structural information, delayed small molecule drug discovery, and scarce fluorescence detection tools a...

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Detalles Bibliográficos
Autores principales: Szalai, A.M., Armando, N.G., Barabas, F.M., Stefani, F.D., Giordano, L., Bari, S.E., Cavasotto, C.N., Silberstein, S., Aramendía, P.F.
Formato: JOUR
Materias:
biological marker
corticotropin releasing factor receptor
corticotropin releasing factor receptor 1
fluorescent dye
antagonists and inhibitors
chemical structure
chemistry
fluorescence imaging
fluorescence microscopy
human
molecular docking
nanotechnology
synthesis
Biomarkers
Fluorescent Dyes
Humans
Microscopy, Fluorescence
Molecular Docking Simulation
Molecular Structure
Nanotechnology
Optical Imaging
Receptors, Corticotropin-Releasing Hormone
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_14639076_v20_n46_p29212_Szalai
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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